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CRO Exam 1 Questions & Answers 2024/2025

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CRO Exam 1 Questions & Answers 2024/2025 Brain gray matter is central/peripheral and white matter is central/peripheral - ANSWERSperipheral central Spinal cord white matter is central/peripheral and gray matter is central/peripheral - ANSWERSperipheral central Where does the spinal cord ...

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  • August 5, 2024
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  • 2024/2025
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CRO Exam 1 Questions & Answers
2024/2025

Brain gray matter is central/peripheral and white matter is central/peripheral - ANSWERSperipheral
central



Spinal cord white matter is central/peripheral and gray matter is central/peripheral - ANSWERSperipheral
central



Where does the spinal cord end in adults? - ANSWERSL1



Where does the spinal cord end in newborns - ANSWERSL3-L4



What is the most common adult primary CNS tumor? - ANSWERSMeningioma 30-35%



What is the 2nd most common adult primary CNS tumor? - ANSWERSGBM 20%



What are the advantages of using IMRT over 3DCRT for CNS tumors? - ANSWERSsparing critical
structures

deliver hot spots in center of tumor



When planning for CNS tumors, what imaging modality is fused with the treatment planning CT and
why? - ANSWERSMRI to delineate target volume



When do the late radiation complications from treating brain and spinal chord neoplasms occur? -
ANSWERS6 months to many years



What is the most common primary malignant CNS tumor in adults? - ANSWERSmalignant gliomas

,What is the most common malignant glioma in the brain? - ANSWERSGBM



What are the two most common presentations of malignant gliomas - ANSWERSheadache seizure



Brainstem gliomas are most common in what type of patients, and when does the incidence peak? -
ANSWERSyoung patients

peaks between 4-6 years



What is the most common benign intracranial tumor in adults? - ANSWERSmeningioma



What is the male:female ratio of meningioma? - ANSWERSF:M = 2:1



Age of incidence for meningioma? - ANSWERS6th & 7th decade



From where do acoustic neuromas arise? - ANSWERSSchwann cells



What two hormones are most commonly secreted from pituitary tumors? - ANSWERSProlactin (30%)

GH (25%)



What is the second most common pediatric CNS tumor? - ANSWERSMedulloblastoma



What percentage of patients have CSF spread at the time of diagnosis of medulloblastoma? -
ANSWERS30-40%



What is CSF? - ANSWERScerebrospinal fluid



When simulating a patient for craniospinal irradiation for medulloblastoma, how is the patient
positioned? (using traditional approach)? - ANSWERSprone extend neck head mask

, How do you calculate the collimator angle of the cranial field to match the divergence of the spine field?
- ANSWERSarctan(.5*length of the superior spinal field/SSD)



When creating a treatment plan using craniospinal irradiation for medulloblastoma, how do you
calculate the couch angle of the spinal field to match the diverging cranial fields? -
ANSWERSarctan(.5*length of cranial field/SAD)



Name two alternate delivery methods for craniospinal irradiation and why would they be employed? -
ANSWERSprotons reduce exit dose

tomotherapy avoid need to match fields



What is Brown-Sequard syndrome and what malignancy is associated with? - ANSWERSipsilateral loss of
motor fine touch sens of pain and temp

primary spinal cord tumors



the CNS includes the ________ and ________ but NOT the peripheral nervous system - ANSWERSbrain

spinal cord



the parenchyma of the brain includes the (3) - ANSWERScerebrum

cerebellum

brainstem



The brain's supporting tissues include - ANSWERSoligodendrocytes

astrocytes

ependymal cells



What percentage of CNS mets to vertebral bodies causes cord compression? - ANSWERS20%



Why is radiation a common treatment for CNS tumors? - ANSWERSSurgery may not be possible

Blood brain barrior prevents chemo

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