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Pharmacology Final - SLCC Questions and Answers 2024
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Pharmacology Final - SLCCHeartburn, Symptoms of GERD, Duodenal ulcers associated with H. Pylori, erosive
esophagitis, antimicrobial effect - answer Indication for Omeprazole (Prilosec)
Action of Omeprazole (Prilosec) - answer suppress gastric acid secretion by specific
inhibition of the H+/K+ ATPase enzyme system at the secretory surface of the gastric
parietal cell. Proton Pump Inhibitor
Gastric Duodenal ulcers, GERD, Hypersecretory conditions (Zollinger-Ellison
syndrome), Aspiration pneumonitis, Heartburn, Acid indigestion. - answer Indication for
Ranitidine (Zantac)
Cautions related to magnesium sulfate and chronic renal failure - answer Kidneys
cannot clear magnesium and it could cause hypermagnesemia. Could cause
dehydration and electrolyte loss from diarrhea.
ABX. Amoxicillin, clarithromycin, tetracycline, metronidazole. Gram-negative. PPI-H2
receptor - antagonist bismuth. - answer Treatment for H. Pylori
block the gastric H,K-ATPase, inhibiting gastric acid secretion. This effect enables
healing of peptic ulcers, gastroesophageal reflux disease (GERD), Barrett's esophagus,
and Zollinger-Ellison syndrome, as well as the eradication of H-pylori as part of
combination regimens. - answer Action of Proton Pump Inhibitors
Replacement for digestive enzymes – answer Pancrelipase/pancreases
IBS-C, chronic/severe constipation, GI perforation, ischemic colitis, Crohn's disease,
diverticulitis, megacolon, chronic or severe constipation - answer Contraindications for
alostron (Latrine)
Adverse effects of Metoclopramide (Reglan) - answerCNS effects. BLACK BOX
WARNING: Severe depression.
Block H2 receptors, which reduces the volume of gastric acid and lowers the
concentration of hydrogen ions in the stomach. - answerAction of H2 inhibitors
Action of Filgrastim (Neupogen) - answerIncrease neutrophils. Stimulates production of
Neutrophils.
Labs to monitor effectiveness of heparin - answerPTT
, inactivating thrombin and preventing the conversion of fibrinogen to fibrin. It also
prevents the formation of a stable fibrin clot in inhibiting the activation of the fibrin
stabilizing factor. - answerAction of Heparin
Dependent on adequate quantities of iron, folic acid, vitamin B12. - answerFactor that
promotes effectiveness of epoetin alfa
Action of alteplase (Activase) - answerbinds to the fibrin in a clot and converts the
plasminogen back to plasmin.
Antidote for Heparin - answerProtamine
prevent clotting by activating antithrombin, indirectly inactivating both thrombin and
factor Xa - answerAction of anticoagulant
bind to the fibrin in a clot and convert the plasminogen back to plasmin. Assist in the
dissolving of a clot. - answerAction of thrombolytics
Drug used for symptomatic bradycardis/anticholinergic - answerAtropine
N/V/D, ABD pain, peripheral vasodilation, salivation, diaphoresis, bradycardia, bronchial
constriction. - answerCholinergic Crisis
Muscle weakness, SOB, difficulty swallowing, respiratory insufficiency, quadriparesis,
quadriplegia. - answerMyasthenia Crisis
A challenge dose of edrophonim (Tension) is given. If the symptoms of a patient with
improves after the dose, it means they needed more cholinergic stimulation and their
standing treatment is inadequate. If there is no relief of symptoms or if an increase in
muscle weakness follows, then the patient is receiving too much. - answerCholinergic
Crisis vs. Myasthenia Crisis
Atropine - answerAntidote for Cholinergic Crisis
Important nursing interventions to remember when administering dopamine -
answerMonitor BP every 15 min. Monitor for extravasation. Correct hypovolemia before
hanging.
Action of Fenoldopam - answerVasodilator. Decrease in BP, Hypotension
Main use for adrenergic drugs - answerFight or flight. A1, A2, B1, B2. Looking for shock.
What type of client should avoid OTC preparations containing phenylephrine? -
answerElderly patients for rebound congestion. HTN.
Most serious adverse effect of insulin - answerHypoglycemia
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