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MLS ASCP Exam Questions and Complete Solutions Graded A+
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  c antigen is most common in blacks and whites; anti-c would be most common reactive - Answer: Rh antibodies show enhanced reactivity with enzyme pretreated cells. The M and Fya antigens are cleaved from enzyme pretreated cells and therefore there would be no reaction between enzyme pretreated...

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  • August 11, 2024
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  • 2024/2025
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MLS ASCP Exam
Questions and
Complete Solutions
Graded A+
Denning [Date] [Course title]

,c antigen is most common in blacks and whites; anti-c would be most common reactive - Answer: Rh
antibodies show enhanced reactivity with enzyme pretreated cells. The M and Fya antigens are cleaved
from enzyme pretreated cells and therefore there would be no reaction between enzyme pretreated
cells and serum containing anti-M or anti-Fya. The incidence of the c antigen is 80% in whites and 96% in
blacks. The incidence of the E antigen is 29% in whites and 22% in blacks. Increased reactivity with
enzyme pretreated cells and incompatible results with 8 of 10 donor units is most likely due to anti-c.



Procainamide - Answer: NAPA



loose clusters of small spherical microconidia, positive urease - Answer: Trichophyton mentagrophytes



BHCG tumor marker - Answer: chorocarcinoma



5HIAA - Answer: carcinoid tumors



Proteus vulgaris vs P. mirabilis indole test - Answer: P. vulgaris is indole pos. P. mirabilis is indole neg



Hydatid cyst fluid - Answer: used to neutralize Anti-P1 antibody



Antacid overdose - Answer: Check pH



Prolonged PT, PTT, and thrombin after collecting from catheter - Answer: heparin contamination



mixing study that was performed with a prolonged PTT that couldn't be corrected - Answer: DRVVT
(Dilute Russell Viper Venom Test)



two pt's ran in duplicate (PT and PTT). The PTT seemed to always be prolonged but PT looked ok -
Answer: check the CaCl/phospholipid reagent delivery



Patient is on coumadin therapy, what will be affected - Answer: Decreased protein C

, Lot's of stomatocytes - Answer: Liver disease



Burr cells - Answer: Uremia



Picture of target cells with hemoglobin C crystals. The white count was high on instrument 1, so a
second instrument was used with a stronger lysing agent, and the white count was corrected - Answer:
anti-lysing target cells are what increased the white count? Erythrocytes containing hemoglobin C do
not lyse normally (sickle cell diseases)



A sodium citrate tube was drawn for a HCT on a pt but the hematocrit was abnormal - Answer: recollect
with decreased anticoagulant. high hct (>55%) causes low plasma so you need less anticoagulant



Question that gives a red blood cells count, HGB, and HCT. I did the rule of 3 and found that the HGB
didn't meet the rule of 3 because it was too high - Answer: check for lipemia (elevates HGB)



PBS with an elevated reticulocyte count and howell jolly bodies in the RBC's - Answer: Prussian blue for
howell jolly bodies made of iron. Prussian blue stain, which is not taken up by reticulocytes, is helpful in
differentiating the two.



what is composed of DNA? - Answer: howell jolly bodies



what falsely increases ESR - Answer: vibration, tilting of tube, higher temps, >1 hr test time, improper
mixing of blood, improper dilution



factors decreasing ESR - Answer: Polycythemia, Microcytosis (Hb C), Sickle cells, spherocytes, Anti-
inflammatory medications, Hypogammaglobulinemia, Hypofibrinogenemia (DIC), High WBC count,
Hyperviscosity



Factors increasing ESR - Answer: Anemia, Macrocytosis, Female gender, Age >50 years, Obesity,
Pregnancy, Hypercholesterolemia, cancer, multiple myeloma, rouleaux, infections, inflammation



what falsely decreases ESR - Answer: low blood/ room temps, air bubbles, tests <1 hr, improper mixing
of blood, improper dilution

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