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2024 AAMC MCAT PRACTICE EXAM 1 WITH CORRECT ANSWERS

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2024 AAMC MCAT PRACTICE EXAM 1 WITH CORRECT ANSWERS

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  • August 12, 2024
  • 67
  • 2024/2025
  • Exam (elaborations)
  • Questions & answers
  • AAMC MCAT
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2024 AAMC MCAT PRACTICE EXAM
1 WITH CORRECT ANSWERS

In the chromatography of the reaction mixture, water absorbed on cellulose
functioned as the stationary phase. What was the principal factor
determining the migration of individual components in the sample?

A) Hydrogen bonding
B) Solute concentration
C) Stationary phase concentration
D) Thickness of paper - CORRECT ANSWERS-A) Hydrogen bonding

The answer to this question is A because the relative amount of hydrogen
bonding to the stationary phase will determine the relative rate of migration
of the various components in the sample.

What type of functional group is formed when aspartic acid reacts with
another amino acid to form a peptide bond?

A) An amine group
B) An aldehyde group
C) An amide group
D) A carboxyl group - CORRECT ANSWERS-C) An amide group

The answer to this question is C because the functional group that forms
during peptide bond formation is known as an amide group.

Which research methodology involves the extended, systematic observation
of a complete social environment?
A) Comparative methods
B) Ethnographic methods
C) Experimental methods
D) Survey methods - CORRECT ANSWERS-B) Ethnographic methods

Ethnographic methods are accurately described in the question as involving
systematic observation of a complete social environment.

comparative methods - CORRECT ANSWERS-researcher collects data about
different social groups (eg working-class; middle-class and upper-class) and
then compares one group with another to identify what is evident in one
group but not another

,Which term refers to closed status positions that hinder social mobility?
A) Class systems
B) Caste systems
C) Economic systems
D) Financial systems - CORRECT ANSWERS-B) Caste systems

The correct answer is B. Caste systems describe closed stratification systems
that do not allow for social mobility.



What assumption is being made if scientists conclude that aspartic acid was
formed by the prebiological synthesis in the passage?

A) Aspartic acid is unstable at temperatures below 150 degrees C.
B) All of the malic acid underwent the dehydration reaction to form
fumaric/maleic acid.
C) Compound A and cyanide were available on primitive Earth.
D) The reaction between ammonia and fumaric acid was catalyzed by the
presence of water. - CORRECT ANSWERS-C) Compound A and cyanide were
available on primitive Earth.

he answer to this question is C since, in order for the experimental reaction
sequence to be relevant to the primordial formation of aspartic acid, the
starting materials used (Compound A and cyanide) are assumed to have
been available.

According to the developed chromatography plate shown below, what is the
approximate Rf value of aspartic acid?

aspartic acid = 2
solvent front = 10

A) 0.20
B) 0.50
C) 5
D) 10 - CORRECT ANSWERS-The answer to this question is A (0.20) because
Rf is the ratio of the distance travelled by the analyte relative to the solvent
front during a chromatographic separation. Aspartic acid travelled two units,
while the solvent front travelled ten units, giving an Rf of 2/10 = 0.20 for
aspartic acid.

Which of the following statements does NOT correctly describe the
dehydration of malic acid to fumaric acid and maleic acid?

A) The reaction occurs most readily with tertiary alcohols.

,B) The reaction involves the loss of a water molecule.
C) The reaction has a carbocation intermediate.
D) The reaction is stereospecific. - CORRECT ANSWERS-D) The reaction is
stereospecific.

The answer to this question is D because the fact that both fumaric and
maleic acid are produced means that the dehydration of malic acid is NOT
stereospecific.


If 2-pentanol replaces 1-pentanol in the reaction shown in Figure 3 (SN2), the
rate of substitution is less because:
A) the C-O bond in 2-pentanol is stronger than the C-O bond in 1-pentanol.
B) there is a competing elimination reaction that slows the rate of
substitution.
C) there is more steric hindrance at the oxygen atom in 2-pentanol than in 1-
pentanol, making protonation less likely.
D) there is more steric hindrance at the 2-position of 2-pentanol than at the
1-position of 1-pentanol. - CORRECT ANSWERS-D) there is more steric
hindrance at the 2-position of 2-pentanol than at the 1-position of 1-
pentanol.

The answer to this question is D because the rate of substitution of
protonated alcohols is subject to steric hindrance. This inhibits the ability of
nucleophiles to collide with the reacting electrophilic center and slows the
rate of reaction.

If a solution containing the compounds shown in Figure 4, is injected into a
gas-liquid chromatograph, the first peak observed in the gc trace is
attributable to which compound?
A) Methyl-2-butanol
B) Methyl-2-butene
C) Chloro-2-methylbutane
D) Bromo-2-mehtylbutane - CORRECT ANSWERS-B) Methyl-2-butene

The answer to this question is B because 2-methyl-2-butene will exhibit the
lowest molecular weight and also the weakest intermolecular forces of
attraction. This substance will therefore migrate the fastest and be the first
peak in the gas chromatograph (gc) trace.

R vs. S stereochemistry* - CORRECT ANSWERS-R = clockwise
C = counter-clockwise

Acetic acid and ethanol react to form an ester product as shown below.

, In determining which reactant loses the -OH group, which of the following
isotopic substitutions would be most useful?

A) Replace the acidic H of acetic acid with D
B) Replace the alcoholic H of ethanol with D.
C) Replace the carbonyl oxygen of acetic acid with O-18.
D) Replace the hydroxyl oxygen of ethanol with O-18. - CORRECT ANSWERS-
D) Replace the hydroxyl oxygen of ethanol with O-18.

The answer to this question is D because this experiment involves labeling a
group which does not exchange with other groups present prior to reaction
and will therefore give information about the true identity of the groups,
which are exchanged during the reaction.

A person whose eye has a lens-to-retina distance of 2.0 cm, can only clearly
see objects that are closer than 1.0 m away. What is the strength S of the
person's eye lens? (Note: Use the thin lens formula 1/O + 1/I = S)

A) -50 D
B) -10 D
C) 51 D
D) 55 D - CORRECT ANSWERS-C) 51 D

The answer to this question is C because the strength of the eye lens is
equal to the inverse of the focal length of the eye lens. Its numerical value is
given by (1 m)-1+(0.02 m)-1=1 D+50 D=51 D.

Which statement correctly describes how enzymes affect chemical
reactions? Stabilization of:

A) the substrate changes the free energy of the reaction.
B) the transition state changes the free energy of the reaction.
C) the substrate changes the activation energy of the reaction.
D) the transition state changes the activation energy of the reaction. -
CORRECT ANSWERS-D) the transition state changes the activation energy of
the reaction.

The answer is D because the stabilization of the transition state, not the
substrate, provides binding energy that is used to lower the activation
energy.

Which of the following will decrease the percentage ionization of 1.0 M acetic
acid, CH3CO2H(aq)?*

A) Chlorinating the CH3 group
B) Diluting the solution

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