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Care of the Organ Donor and Transplant Recipient (1) Questions & 100% Verified Correct Answers with complete solutions (Latest update

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Care of the Organ Donor and Transplant Recipient (1) Questions & 100% Verified Correct Answers with complete solutions (Latest update

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  • August 14, 2024
  • 13
  • 2024/2025
  • Exam (elaborations)
  • Questions & answers

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  • care of the organ donor and transplant recipient

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Care of the Organ Donor and Transplant Recipient
results in the stimulation of T lymphocyte activity
usually triggered by antigens like viral infected cells, cancer cells, and foreign tissue - ANS-cell
mediated response

results in stimulation of B lymphocyte activity
followed by inflammation and phaygocytosis
usually triggered by bacteria, bacterial toxins, and some viruses - ANS-antibody mediated
(humoral) response

substances that are recognized by the body as foreign or nonself
HLA antigens found on Chromosome 6 help the immune system determine what tissue is
foreign and what is self - ANS-antigens

used to determine how much overlap exists between a potential donor's and the recipient's HLA
antigen
complete matches only occur with identical siblings - ANS-tissue typing

antihuman antibodies in the blood that would react with the tissue of a potential donor
results in loss of the transplanted organ - ANS-hyperacute rejection

O blood - ANS-universal donar

AB blood - ANS-universal recipient

decreases the risk of organ rejection because it can be scheduled in advance, the recipient can
begin taking immunosuppressant drugs a day or two before surgery, usually a better tissue
match - ANS-living donors

physically fit
in good general health
free from high blood pressure, diabetes, cancer, kidney disease, heart disease and a variety of
infectious diseases like HIV and TB
older than 18 - ANS-qualifications for a living kidney donor

tissue typing: blood drawn for HLA typing
crossmatching: done just before transplant to prevent hyperacute rejection
antibody screening: blood test determines if antibodies can react to donor's antigens
screening for transmissible diseases: blood test to determine if donor has HIV/AIDS, cancer,
hepatitis
renal function: serum creatinine, urea, electrolytes, urinary sediment, albuminuria, creatinine
clearance and glycosuria

, renal structure: renal ultrasound and angiogram
psychiatric/psychological evaluation - ANS-testing for donation

must donate voluntarily
give plenty of opportunities to change mind
*risk of death low for kidney and liver donation - ANS-ethical kidney donation issues

movement is essential-encourage to get out of bed several hours after surgery
remain in hospital 4-8 days after surgery
no heavy lifting, rough contact sports for 6 wks
return to work in 4wks - ANS-post surgery care of living donors

used more frequently, smaller incision, less pain, better cosmetic results, shorter recovery time
discharged in 1-2 days
takes 3 months to feel like themselves again
watch for signs of depression, anxiety attacks, suicidal tendancies - ANS-post laparoscopy care
of living donors

good health previously
less than 70 - ANS-qualifications of deceased donor

uncontrolled sepsis
active viral infection
HIV positive serology
any malignancy except a primary intracranial tumor - ANS-contraindications to donation

donation after brain death
donation after cardiac death - ANS-two types of donation from deceased donor

patient who has had a severe acute brain injury who requires mechanical ventilation and is in
the ICU or ED
has clinical findings on GCS below 5
had withdrawal of life sustaining treatment ordered by physician
being evaluated for diagnosis of brain death - ANS-definition of imminent death

the irreversible loss of function of the brain, including brainstem, or irreversible loss of circulatory
or respiratory function - ANS-brain death

severe head trauma
rupture of the cerebral aneurysm
hypoxic ischemic brain insults
fulminate hepatic failure - ANS-common causes of brain death

evidence of acute neuro catastrophe, CT scan used to determine cause of brain death

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