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EPPP- Neurocognitive Disorders (PrepJet)
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EPPP- Neurocognitive Disorders (PrepJet) What criteria is required to diagnose major neurocognitive disorder probable Alzheimers? ️evidence of a causative genetic mutation from genetic testing or family history and/or evidence of a decline in memory and learning and at least one other cogni...

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  • August 15, 2024
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  • 2024/2025
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EPPP- Neurocognitive Disorders (PrepJet)
What criteria is required to diagnose major neurocognitive disorder probable Alzheimers? ✔️evidence
of a causative genetic mutation from genetic testing or family history and/or evidence of a decline in
memory and learning and at least one other cognitive domain, a steadily progressive and gradual
decline in cognition, and no evidence of a mixed etiology



What is the age of of early onset Alzheimer's? ✔️the early-onset subtype applying to individuals whose
symptoms had an onset at 65 year of age or younger.



What does the term pseudodementia refer to? ✔️depression that has prominent cognitive symptoms.



How do people with pseudodementia respond to treatment? ✔️people with pseudodementia usually
respond well to treatment, and they have an abrupt onset of symptoms, exaggerate their cognitive
problems, have moderate memory loss and symptoms of melancholia and anxiety, and often say "I don't
know in response" to assessment questions. I



What are genetic risks for Alzheimer's? ✔️the ApoE4 variant on chromosome 19.



What are neurotransmitter abnormalities in Alzheimer's? ✔️reduced acetylcholine (ACh) and excessive
glutamate, which are both known to be involved in learning and memory.



What are the areas in the brain first affected by Alzheimer's? ✔️here's also evidence that the locus
coeruleus (an area in the brain stem) is the first area of the brain to be affected by Alzheimer's disease
and shows abnormalities before the appearance of symptoms. Then, the temporal lobe.



Describe the early stages of Alzheimer's ✔️The early stage lasts for about two to four years and
involves anterograde amnesia, personality changes and mood disturbances, impaired attention and
judgment, and anomia (difficulty recalling names of familiar people and objects).



Describe the middle stages of Alzheimer's ✔️he middle stage which lasts for two to 10 years. Its
symptoms include increasing anterograde and retrograde amnesia, disorientation to time and place,
anxiety or depression, delusions, wandering and pacing, compulsive and repetitive behaviors, impaired
speech, disruption in sleep patterns, and problems with normal daily activities.

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