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Exam (elaborations)

NRNP 6675 Week 6 final Exam Questions and Verified Answers (2024 / 2025) 100% Guarantee Pass

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NRNP 6675 Week 6 final Exam Questions and Verified Answers (2024 / 2025) 100% Guarantee Pass

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  • August 15, 2024
  • 33
  • 2024/2025
  • Exam (elaborations)
  • Questions & answers
  • NRNP 6675
  • NRNP 6675
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NRNP 6675 FINAL EXAM LAST EXAM EVERRRRR (minus boards)




1.The 1/2 life of lithium is about?: 24 hours

2.Fluoxetine is the SSRI with the WD risk?: lowest due to long half life

3.What antipsychotics are good for pts who miss doses of their meds?: An-

tipsychotics with long half-lives:

1.Cariprazine(Vrylar): (2-4 days-active metabolites up to 3 weeks)

2.Abilify (3 days)

3.Brexipiprazole (4 days)

4.Pimozide (4-5 days)

5.Pimavanserin (2 days, active metabolites 8 days)

4.Disulfiram's alcohol interactions persist for up to how long after the med-

ication is stopped?: LONG Half life--2-3 days


persist up to 2 weeks following stopping

5.What is the only TCA with a long half life?: Protriptyline (Vivactil)

6.Most psychotropics have a medium range 1/2 life of approx?: 24 hours

7.what does "steady state" mean in relation to 1/2 life?: steady state means that

you are eliminating the drug at the same overall rate that you are ingesting it

8.Lithium reaches its 'steady state' when?: 5 half lives



, NRNP 6675 FINAL EXAM LAST EXAM EVERRRRR (minus boards)

example:

Day 1: Start pt on Lithium 600 mg daily

Day 2: (24 hours later) the amount left in his body is 300 mg (day 2 min) because 24

hours has passed--one 1/2 life--therefore the pt has excreted 1/2 of the initial

amount.

THEN the pt takes his 2nd dose of 600 mg on DAY 2-resulting in a max dose of 900

(300 mg left in body + 600 mg of 2nd dose).

DAY 3: starts off with 450 mg (1/2 of the 900 mg in pt's system) and after taking the

day 3 600 mg dose, the pt now has a total of 1050 mg.

9.Due to the steady state of Lithium, when do we draw a blood level?: 5 half

lives


if you check any earlier, the trough level will underestimate the actual level the pt is

on after achieving steady state

10.Fluoxetine has a half life of about?: 2 weeks 1/2 life


take 2.5 months to achieve steady state

11.Most psychotropic medications operate in this fashion:: "when you double

the dose, the serum dose doubles."





, NRNP 6675 FINAL EXAM LAST EXAM EVERRRRR (minus boards)




*minus three SRIs and three anticonvulsants (Fluoxetine, fluvoxamine, paxil,

gabapentin, valproate and carbamazepine)

12. induces it's own metabolism, hastening excretion and shorten-

ing it's half life: A. Carbamazepine (Tegretol)


*this effect begins to "rev up" after 2-4 weeks--which is why a carbamazepine level is

so important on obtaining 1-2 months after starting Tegretol.

13.Carbamazepine (Tegretol) level should be checked how soon after starting

to take this med?: 1-2 months due to Tegretol inducing it's own metabolism,

hastening excretion and shortening it's half life.

14. has trouble getting a "serum" level because it binds to proteins that

render it therapeutically inactive?: A. Valproate Acid (Depakote)


-this is particularly true at the lower levels (eg. <50 mcg/mL), so you can expect dose

changes to make a more dramatic difference when the pt's depakote level is in the

higher range

15. 's serum level is the opposite of Valproic Acid: it rises quickly at

first and then slows down?: Gabapentin




, NRNP 6675 FINAL EXAM LAST EXAM EVERRRRR (minus boards)

*gabapentin saturates the transporters that absorb it in the small intestine, causing

its levels to rise at a snails pace when the dosage goes above a certain saturation

point (around 900 mg/day).


-from there, the saturation trickles down; @ 900 mg/day--60% is absorbed. @ 1200

mg/day--50 % is absorbed. @3000 mg/day--30% of the gabapentin is absorbed.

16.Due to Gabapentin's serum pattern for dosage:

@ 900 mg/day, how much is the patient absorbing?: @ 0900mg/day---60% is

absorbed.

17.Due to Gabapentin's serum pattern for dosage:

@ 1200 mg/day, how much is the patient absorbing?: @ 1200 mg/day--50 % is

absorbed.

18.Due to Gabapentin's serum pattern for dosage:

@ 3000 mg/day, how much is the patient absorbing?: @3000 mg/day--30% of the

gabapentin is absorbed.

19.Carbamazepine (Tegretol's) serum level drops after how long after stop-

ping taking it?: 1-2 months

20.For Valproate (Depakote), dose changes can have big effects once the

level is beyond 50 mcg/mL?: SMALL

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