100% satisfaction guarantee Immediately available after payment Both online and in PDF No strings attached
logo-home
BIO 235 Exam 4 questions and answers CA$19.56   Add to cart

Exam (elaborations)

BIO 235 Exam 4 questions and answers

 8 views  0 purchase
  • Course
  • BIO 235
  • Institution
  • BIO 235

Helicase - Unwinds DNA in both directions Gyrase - topoisomerase that relieves supercoiling ahead of replication fork Single Stranded Binding proteins do what? - Stabilize single stranded DNA Primase - Enzyme that makes RNA primers DNA polymerase cannot? - Reconstruct the 5' end of a DN...

[Show more]

Preview 2 out of 15  pages

  • August 29, 2024
  • 15
  • 2024/2025
  • Exam (elaborations)
  • Questions & answers
  • BIO 235
  • BIO 235
avatar-seller
BIO 235 Exam 4 questions and answers
Helicase - Unwinds DNA in both directions


Gyrase - topoisomerase that relieves supercoiling ahead of replication fork


Single Stranded Binding proteins do what? - Stabilize single stranded DNA


Primase - Enzyme that makes RNA primers


DNA polymerase cannot? - Reconstruct the 5' end of a DNA strand


this poses problems for linear chromosome integrity


Telomeres - Repetitive DNA sequences TTAGGG
-no protein coding
-binds two types


Two types of proteins that binds in telomeres - -Protective proteins
-telomerase enzyme


Telomerase enzyme - ribonucleoprotein


ribonucleoprotein - composed of RNA and protein

, Binding of telomerase to TTAGGG - Addition of RNA extends ends
-carries its own DNA template as well....to finish DNA strand


Telomerase is key in determining what? - Life-span of cell


Telomerase in immortalized cells - ie germ line, cancer, yeast...


-Telomeres are fully reconstructed with each DNA replication


Telomerase in somatic cells - Virtually absent
-shortened with every cell division
-somatic cells divide 30-50 times then die


in yeast, deletion of telomerase gene leads to what? - Shortening of chromosomes
at each cell division


Telomerase activity in cancer cells? - High activity


Telomerase activity in somatic cells which cancer derives? - low activity or absent


If you can block telomerase activity, you can do what? - STOP CANCER!


Nobel prize in medicine: - Elizabeth Blackburn, Carol Greider, Jack Szostak.


-Protection of chromosomes by the telomerase enzyme

The benefits of buying summaries with Stuvia:

Guaranteed quality through customer reviews

Guaranteed quality through customer reviews

Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.

Quick and easy check-out

Quick and easy check-out

You can quickly pay through credit card or Stuvia-credit for the summaries. There is no membership needed.

Focus on what matters

Focus on what matters

Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!

Frequently asked questions

What do I get when I buy this document?

You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.

Satisfaction guarantee: how does it work?

Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.

Who am I buying these notes from?

Stuvia is a marketplace, so you are not buying this document from us, but from seller CleanA. Stuvia facilitates payment to the seller.

Will I be stuck with a subscription?

No, you only buy these notes for CA$19.56. You're not tied to anything after your purchase.

Can Stuvia be trusted?

4.6 stars on Google & Trustpilot (+1000 reviews)

75632 documents were sold in the last 30 days

Founded in 2010, the go-to place to buy study notes for 14 years now

Start selling
CA$19.56
  • (0)
  Add to cart