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NAPLEX MOA BEST GRADED EXAM QUESTION LATEST VERSION 2024
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adapalene - CORRECT ANSWER-topical retinoid for acne brimonidine ophth (Alphagan) - CORRECT ANSWER-adrenergic alpha-2 agonist for glaucoma (reduce aqueous humor production and increase aqueous outflow) phenazopyridine (pyridium) - CORRECT ANSWER-Urinary analgesic to treat dysuria (pain or bur...

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  • August 31, 2024
  • 79
  • 2024/2025
  • Exam (elaborations)
  • Questions & answers

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  • naplex moa best graded exam question latest versio
  • naplex moa best graded exam question stuvia
  • adapalene correct answer topical retinoid for ac

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NAPLEX MOA BEST GRADED EXAM
QUESTION LATEST VERSION 2024

adapalene - CORRECT ANSWER-topical retinoid for acne



brimonidine ophth (Alphagan) - CORRECT ANSWER-adrenergic alpha-2 agonist for
glaucoma (reduce aqueous humor production and increase aqueous outflow)



phenazopyridine (pyridium) - CORRECT ANSWER-Urinary analgesic to treat dysuria
(pain or burning with urination) during UTI



testosterone topical (Androgel) - CORRECT ANSWER-testosterone replacement for
hypogonadism



gatifloxacin (zymar) - CORRECT ANSWER-quinolone antibiotic (inhibit bacterial DNA
topo IV and DNA gyrase which prevents supercoiling of DNA and promotes breakage of
ds DNA)



moxifloxacin ophthalmic (vigamox) - CORRECT ANSWER-quinolone antibiotic (inhibit
bacterial DNA topo IV and DNA gyrase which prevents supercoiling of DNA and
promotes breakage of ds DNA)



clindamycin - CORRECT ANSWER-lincosamide antibiotic (binds to 50S subunit of the
bacterial ribosome inhibiting protein synthesis)



mupirocin topical - CORRECT ANSWER-Topical Antibiotic for eradication and minor
wounds



carbamazepine - CORRECT ANSWER-Narrow-spectrum antiepileptic/Na channel
blocker (decreases neurons firing rate)

Used in epilepsy

Used as pain mgmt adjuvant (neuropathic)

,lacosamide (vimpat) - CORRECT ANSWER-Narrow-spectrum antiepileptic (stabilizes
hyperexcitable neuronal membranes and inhibits repetitive neuronal firing by enhancing
the slow inactivation of Na channels)



lamotrigine - CORRECT ANSWER-Broad-spectrum antiepileptic/Na channel blocker
(decreases neurons firing rate)

Used for focalized and generalized seizures

Used in bipolar depression



levetiracetam - CORRECT ANSWER-Broad-spectrum antiepileptic (Increases GABA
and is also a Ca channel blocker = slows down or stops transmission of the electrical
signal)

Used for focalized and generalized seizures



oxcarbazepine (trileptal) - CORRECT ANSWER-Narrow-spectrum antiepileptic/Na
channel blocker (decreases neurons firing rate)/Ca channel blocker (slows down or
stops transmission of the electrical signal)



topiramate - CORRECT ANSWER-Broad-spectrum antiepileptic/Na channel blocker
(decreases neurons firing rate)

Used for focalized and generalized seizures

Antimigraine ppx agent



divalproex (depakote) - CORRECT ANSWER-Antiepileptic (increases GABA)

Antimigraine ppx agent



phenobarbital - CORRECT ANSWER-Narrow-spectrum antiepileptic/barbiturate
(enhances GABA effect)



phenytoin oral/injection (dilantin) - CORRECT ANSWER-Narrow-spectrum
antiepileptic/Na channel blocker (decreases neurons firing rate)

,pregabalin oral - CORRECT ANSWER-Miscellaneous antiepileptic

Not really used in epilepsy

Used as pain mgmt adjuvant (neuropathic)

Also used for anxiety



gabapentin (neurontin) - CORRECT ANSWER-Miscellaneous antiepileptic/GABA
analog (However, it does not bind to GABA-A or GABA-B receptors, & does not appear
to influence synthesis or uptake of GABA. High affinity gabapentin binding sites in the
brain correspond to the presence of voltage-gated Ca channels specifically possessing
the alpha-2-delta-1 subunit. This channel is located presynaptically, and may modulate
the release of excitatory NTs which participate in epileptogenesis & nociception)

Used in epilepsy

Used as pain mgmt adjuvant (neuropathic)



diphenoxylate/atropine - CORRECT ANSWER-Antidiarrheal agents (diphenoxylate is an
antimotility agent that slows intestinal motility prolong water reabsorption in the gut.
Atropine is an anticholinergic agent)

Used for diarrhea and IBS-D



metoclopramide (reglan) - CORRECT ANSWER-Antiemetic agent/DA receptor
antagonist (blocks DA receptors int he CNS including the CTZ. Also enhances response
to ACh in the upper GI tract, causing enhanced motility, accelerated gastric emptying
and increase LES tone which decreases GERD sx)

Used in CINV

Also used in GERD + gastroparesis



nystatin topical - CORRECT ANSWER-miscellaneous systemic nonabsorbed/Partially
Absorbed antifungal agent (Binds to sterols in fungal cell membrane, changing the cell
wall permeability allowing for leakage of cellular contents)



clotrimazole/betamethasone topical - CORRECT ANSWER-antifungal agent for fungal
skin infections (athletes foot, jock itch, ringworm, candida)

, colchicine - CORRECT ANSWER-Antigout Agent (disrupts cytoskeletal functions by
inhibiting β-tubulin polymerization into microtubules, preventing activation,
degranulation, and migration of neutrophils associated with mediating some gout
symptoms)



hydrocortisone topical (proctocort, cortaid, cortizone) - CORRECT ANSWER-for rectal
or skin conditions

proctocort (rectal), cortaid (rectal), cortizone (skin)



anastrozole (arimidex) - CORRECT ANSWER-Aromatase inhibitor (decreases
production of estrogen and testosterone)

Used in breast cancer



benzonatate - CORRECT ANSWER-Cough suppressant (for nonproductive cough) for
cough/cold (suppresses cough by anesthetic action on the respiratory stretch receptors)



hydrocodone/chlorpheniramine - CORRECT ANSWER-mu-opioid receptor agonist/1st
generation antihistamine

Used for temporary relief of cough and upper respiratory tract symptoms associated
with allergy or the common cold



alendronate oral (fosamax) - CORRECT ANSWER-bisphosphonate (inhibit osteoclast
activity and bone resorption)

Used for osteoporosis



ibandronate oral/injection (boniva) - CORRECT ANSWER-bisphosphonate (inhibit
osteoclast activity and bone resorption)

Used for osteoporosis



risedronate oral (actonel) - CORRECT ANSWER-bisphosphonate (inhibit osteoclast
activity and bone resorption)

Used for osteoporosis

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