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Smarty Pance Questions and Answer | Latest Update 2024/2025
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Which of the following pathophysiological processes is associated with chronic bronchitis A. Destruction of the lung parenchyma B. Mucous gland enlargement and goblet cell hyperplasia C. Smooth muscle hypertrophy in the large airways D. Increased mucus adhesion secondary to reduction in the s...

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  • September 16, 2024
  • 91
  • 2024/2025
  • Exam (elaborations)
  • Questions & answers

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  • smarty pance questions and answer latest update
  • which of the following pathophysiological processe

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1 | P a g e | © copyright 2024/2025 | Grade A+




Smarty Pance Questions and
Answer | Latest Update 2024/2025
Which of the following pathophysiological processes is associated with

chronic bronchitis


A. Destruction of the lung parenchyma


B. Mucous gland enlargement and goblet cell hyperplasia


C. Smooth muscle hypertrophy in the large airways


D. Increased mucus adhesion secondary to reduction in the salt and water

content of the mucus


✓ ~~> B. Mucous gland enlargement and goblet cell hyperplasia




A 65-year-old with COPD having received their first PPSV23 vaccination at

age 63 should be revaccinated with PPSV23 in


A. 1 year


B. 3 years


C. 5 years


D. 10 years


✓ ~~> C. 5 years




Master01 | September, 2024/2025 | Latest update

, 2 | P a g e | © copyright 2024/2025 | Grade A+


A patient with severe COPD presents to the Emergency Department with a 3

day history of increasing shortness of breath with exertion and cough

productive of purulent sputum. An arterial blood gas reveals a pH of 7.25,

PaCO2 of 70 mmHg and PaO2 of 50 mmHg. He is started on albuterol

nebulizer, nasal oxygen at 2 liters per minute, and an IV is started. After one

hour of treatment, his arterial blood gas now reveals a pH of 7.15, PaCO2 100

mmHg and PaO2 of 70 mmHg. Which of the following is the most appropriate

next step in his treatment?


A. Decrease the oxygen flow rate.


B. Administer oral corticosteroids.


C. Intubate the patient.


D. Administer salmeterol (Serevent)


✓ ~~> C. Intubate the patient




A 73-year-old obese female with a 20 pack year smoking history presents

complaining of chronic productive cough. She states that it has been

occurring over the past 3 years more frequently November through February.

Which of the following pulmonary function test values would you expect to

find decreased?


A. tidal volume


B. forced expiratory volume in 1 second/forced vital capacity



Master01 | September, 2024/2025 | Latest update

, 3 | P a g e | © copyright 2024/2025 | Grade A+


C. residual volume


D. total lung capacity


✓ ~~> B. forced expiratory volume in 1 second/forced vital capacity

(Obstructive lung disease)




A 75 year-old man with a long history of COPD presents with acute onset of

worsening dyspnea, increased productive cough, and marked agitation.

While in the emergency department he becomes lethargic and obtunded.

His ABG's reveal a PaO2 40 mmHg, PaCO2 65 mmHg, and arterial pH 7.25.

Which of the following is the most appropriate management at this point?


A. oxygen supplementation with a 100% non-rebreather mask


B. noninvasive positive pressure ventilation (NIPPV)


C. endotracheal intubation and mechanical ventilation


D. emergency tracheostomy


✓ ~~> C. endotracheal intubation and mechanical ventilation




In patients with COPD, which of the following has been shown to decrease

rate of malignancy and cardiovascular disease and improve survival?


A.bronchodilator therapy


B. pulmonary rehabilitation



Master01 | September, 2024/2025 | Latest update

, 4 | P a g e | © copyright 2024/2025 | Grade A+


C. oral glucocorticosteroids


D. smoking cessation


✓ ~~> D. smoking cessation




A 45 year-old male presents with complaints of a chronic cough productive

of mucopurulent sputum. The cough has been present for the past 3 years,

but he attributed it to a "smoker's cough". He has been coughing up a lot of

sputum lasting all winter long for the past 2 years. He denies any hemoptysis,

weight loss or chest pain. Physical examination reveals a moderately obese

male in no acute respiratory distress. Lung fields reveal presence of scattered

rhonchi and wheezes. There is 1+ peripheral edema. Which of the following is

the most likely diagnosis?


A. Lung cancer


B. Bronchiectasis


C. Chronic bronchitis


D. Interstitial lung disease


✓ ~~> C. Chronic bronchitis




A 56 year-old male with a 40 pack-year smoking history presents complaining

of progressive shortness of breath. Spirometry reveals an FEV1 of 2 L (40% of




Master01 | September, 2024/2025 | Latest update

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