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Bio467 Exam 2 – Neurodevelopment Questions and Answers
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Bio467 Exam 2 – NeurodevelopmentQuestions and Answers
Pattern iiformation ii- iiCorrect iiAnswers ii-The iiprocess iiby iiwhich iigroups iiof iicells iiadopt
iidistinct iifates iiduring iidevelopment
Commitment ii- iiCorrect iiAnswers ii-The iirestriction iiof iia iicell's iidevelopmental iifate ii-
iisubtle, iiinvolves iichanges iiin iigene iiexpression
Differentiation ii- iiCorrect iiAnswers ii-The iigeneration iiof iia iispecialized iicell iitype iifrom
iicommitted iiprecursors ii- iichanges iiin iifunctional/morphological iifeatures
Gastrulation ii- iiCorrect iiAnswers ii-the iitransformation iiof iithe iiblastula ii(early iisheet iiof
iiES iicells) iito iiproduce iithe ii3 iigerm iilayers
What iiare iithe ii3 iigerm iilayers iithat iiderive iifrom iithe iiepiblast? ii(outer iito iiinner) ii-
iiCorrect iiAnswers ii-Ectoderm, iimesoderm, iiendoderm
Which iigerm iilayer iigenerates iithe iinervous iisystem? ii- iiCorrect iiAnswers ii-Ectoderm
What iiis iineurulation? ii- iiCorrect iiAnswers ii-Transformation iiof iia iiregion iiof iithe
iiectoderm iiinto iithe iineural iitube/plate
Describe iineural iitube iiclosure. ii- iiCorrect iiAnswers ii-- iiNeural iiplate iifolds iiin iiand iifuses
iiat iithe iidorsal iilip iito iiform iithe iineural iitube
- iiNeural iitube iigenerates iia iineuroepithelium ii(makes iithe iiCNS)
- iiDorsal iilip iiof iithe iineural iitube iigenerates iithe iineural iicrest ii(makes iithe iiPNS)
What iiis iianencephaly? ii- iiCorrect iiAnswers ii-Rostral iineural iitube iiclosure iidefect ii-
iileads iito iideformity iiin iiwhich iisome iior iiall iiof iifetal iibrain iiis iimissing
What iiis iispina iibifida? ii- iiCorrect iiAnswers ii-Caudal iineural iitube iiclosure iidefect ii-
iidefects iiin iithe iilumbar iispinal iicolumn iicaused iiby iiimperfect iiunion iiof iivertebral iiparts
Role iiof iifolates iiin iineural iitube iiclosure? ii- iiCorrect iiAnswers ii-Studies iisuggest iiit
iipromotes iineural iitube iiclosure ii- iifolate iifortification iiis iiassociated iiwith iisignificant
iidecreases iiin iiNTDs
, What iiis iiEMT ii(epithelial-mesenchymal iitransition)? ii- iiCorrect iiAnswers ii-Process
iiwhere iistem iicells iiin iidorsal iilip iiof iineural iitube iitransform iiinto iimigratory iineural iicrest
What iiis iineurogenesis? ii- iiCorrect iiAnswers ii-formation iiof iinew iineurons iifrom iineural
iistem iicells
What iiis iigliogenesis? ii- iiCorrect iiAnswers ii-formation iiof iiperipheral iiglia iifrom iineurons
Example iiof iicells iiformed iiby iigliogenesis? ii- iiCorrect iiAnswers ii-Schwann iicells,
iiastrocytes, iioligodendrocytes, iiependymal iicells
What iiforms iithe iiCNS? ii- iiCorrect iiAnswers ii-neural iitube
What iiforms iithe iiPNS? ii- iiCorrect iiAnswers ii-neural iicrest
How iidoes iithe iineural iitube iiturn iiinto iithe iispinal iicord? ii- iiCorrect iiAnswers ii-After
iineural iitube iiclosure, iidividing iineuroepithelial iiprogenitors ii(NEPs) iisurround iithe
iicentral iicanal ii(future iiventricular iisystem) iiin iithe iiventricular iizone ii(VZ)
Describe iineuroepithelial iiprogenitor ii(NEP) iiproliferation. ii- iiCorrect iiAnswers ii-- iiNEP
iihas iia iismall iiprocess iiat iithe iipill iiand iiventricular iisurface iiof iithe iiventricular iizone
- iiNEP iisoma iimove iialong iithis iiprocess ii- iiknown iias iiinter iikinetic iinuclear iimigration
- iiMitosis iioccurs iiwhen iisoma iiis iiat iithe iiventricular iisurface
What iigenerates iiradial iiglia? ii- iiCorrect iiAnswers ii-NEPs
Where iiare iiradial iiglia iifound? ii- iiCorrect iiAnswers ii-Developing iiCNS
Function iiof iiradial iiglia? ii- iiCorrect iiAnswers ii-Direct iineurogenesis iiby
iisupporting/guiding iimigrating iineurons
Immature iineurons iidivide iifrom ii___ iiin iithe iiventricular iizone. iiImmature iineurons
iiutilize ii___ iialong iiradial iiglia iifibers. ii- iiCorrect iiAnswers ii-Radial iiglia, iiradial iimigration
How iiis iithe iidorso-ventral iiaxis iiof iithe iispinal iicord iipatterned? ii- iiCorrect iiAnswers ii--
iiNeural iiprogenitor iiprogeny iimigrate iioutward iiradially iifrom iithe iiventricular iizone iiinto
iithe iimantle iizone iiAKA iiprogenitor iidomain. iiMigration iiis iiguided iiby iiradial iiglia
- iiSensory iineurons iiarise iiin iidorsal iidomains iinear iiroofplate
- iiMotor iineurons iiarise iiin iiventral iidomains iinear iifloor iiplate iiand iinotochord
Role iiof iinotochord iiin iineurulation ii- iiCorrect iiAnswers ii-The iinotochord iiventralizes iithe
iineural iitube
Effect iiof iiimplanting iian iiextra iinotochord iiin iithe iineural iitube? ii- iiCorrect iiAnswers ii-
Converts iithe iilateral iineural iitube iiinto iimore iiventral iistate
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