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BIOLOGY 2B03 - Cell Biology Midterm 1 exam tips (possible questions and answer) new update McMaster University CA$18.67   Add to cart

Exam (elaborations)

BIOLOGY 2B03 - Cell Biology Midterm 1 exam tips (possible questions and answer) new update McMaster University

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  • Course
  • BIOLOGY 2B03 - Cell Biology
  • Institution
  • BIOLOGY 2B03 - Cell Biology

BIOLOGY 2B03 - Cell Biology Midterm 1 exam tips (possible questions and answer) new update McMaster University

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  • October 4, 2024
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  • 2024/2025
  • Exam (elaborations)
  • Questions & answers
  • BIOLOGY 2B03 - Cell Biology
  • BIOLOGY 2B03 - Cell Biology
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BIOLOGY 2B03 - Cell Biology
Midterm 1 exam tips (possible
questions and answer) new update
McMaster University

, Problems in normal protein folding mechanisms lead to? - --fibril formation



Examples of 3 general problems in protein folding? - --1) mutation

2) old age

3) prion infection



examples of 4 more specific problems leading to fibril formation - --1) Genetic amyloid- related
diseases: single change in nucleotide lead to changed AA and unstable intermediates

2) Protein fragments do not fold into proper globular form

3) Breakdown of chaperone system

4) Infection by misfolded fibril structures



examples of prion-based diseases - --Mad Cow disease

Creutzfield-Jacob disease

Fatal Familial Insomnia



Hereditary diseases related to improper protein folding - --Alzheimer's disease

Tay-Sachs

Cystic Fibrosis



UPR in response to? - --Unfolded Protein Response; accumulation of misfolded proteins



Prolonged UPR =? - --Cell apoptosis (death)



Modes of prion acquisition? - --1) Spontaneous

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