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Ovarian Tumors (Pathoma + Mahmoud): Questions & Answers CA$15.91   Add to cart

Exam (elaborations)

Ovarian Tumors (Pathoma + Mahmoud): Questions & Answers

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  • PATHOMA
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  • PATHOMA

Ovarian Tumors (Pathoma + Mahmoud): Questions & Answers

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  • October 5, 2024
  • 9
  • 2024/2025
  • Exam (elaborations)
  • Questions & answers
  • PATHOMA
  • PATHOMA
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Ovarian Tumors (Pathoma + Mahmoud): Questions &
Answers

What are the 3 cell types that compose the ovary? Right Ans - surface
epithelium

germ cells

sex cord stroma

What is the most common type of ovarian tumor? Right Ans - surface
epithelial tumor = 70% of cases

What are the 2 most common subtypes of surface epithelial tumors? Right
Ans - serous
mucinous

What are the characteristics of benign (cystadenoma) serous surface
epithelial tumors? Right Ans - composed of a single cyst with a simple, flat
lining

Most commonly in premenopausal/young women = 30-40 years old

What are the characteristics of malignant (cystadenocarcinoma) serous
surface epithelial tumors? Right Ans - composed of *complex* cysts with a
thick, shaggy lining

Most commonly in postmenopausal/older women = 60-70 years old

What are characteristics of borderline serous surface epithelial tumors?
Right Ans - features in between benign and malignant tumors -- *better
prognosis* than clearly malignant tumors, but still carry metastatic potential
=> *development of low grade serous carcinoma*

*bilateral* -- confined to the ovaries

Pts who are carriers of what mutation have an increased risk for serous
carcinoma of the ovary and fallopian tube? Right Ans - BRAC1

, What are risk factors of ovarian neoplasms? Right Ans - nulliparity
FH
heritable mutations: BRAC1 and BRAC2

What lowers the risk of ovarian neoplasms? Right Ans - previous
pregnancy
history of breastfeeding
OCPs, tubal ligation

What are common symptoms of ovarian neoplasms? Right Ans - abdominal
pain and distention
urinary and gastrointestinal tract
pleural effusion
abdominal and vaginal bleeding

How are ovarian neoplasms monitored? Right Ans - monitor progression
by measuring *CA-125 levels* (not good for screening)

What do surface epithelial tumors originate from? Right Ans - *coelomic
epithelium* that lines the ovary

What is the pathogenesis of surface epithelial tumors? Right Ans - repeated
ovulation and scarring, surface epithelium becomes entrapped in the cortex
forming *small epithelial cysts*

What are the most common of all surface epithelial tumors? Right Ans -
serous tumors (borderline and malignant are the most common serous
tumors)

Gross morphology of surface epithelium serous cystadenoma Right Ans -
large cysts, thin walled, smooth surface
one cysts (unilocular) or multiple cysts
filled with clear serous fluid

Histology of surface epithelium serous cystadenoma Right Ans - single
layer of columnar epithelium (ciliated)

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