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NR606 Week 4 || with A+ Guaranteed Solutions.
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  • NR606

develop schizophrenia correct answers -Many genes play a role • as do epigenetic factors • Heritability as high as 79% -gene-environment interaction -Environmental Triggers: • Regular Cannabis Use • Exposure to Early Life Trauma Sexual Abuse Emotional Abuse Emotional Neglect Bully...

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Document information

  • October 13, 2024
  • 14
  • 2024/2025
  • Exam (elaborations)
  • Questions & answers

Subjects

  • develop schizophrenia

Written for

  • NR606
  • NR606

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FullyFocus

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NR606 Week 4 || with A+ Guaranteed Solutions.
develop schizophrenia correct answers -Many genes play a role
• as do epigenetic factors
• Heritability as high as 79%
-gene-environment interaction
-Environmental Triggers:
• Regular Cannabis Use
• Exposure to Early Life Trauma
➣Sexual Abuse
➣Emotional Abuse
➣Emotional Neglect
➣Bullying

schizophrenia Neuroanatomy correct answers -Mesocortical & ventromedial prefrontal cortex:
negative and affective symptoms

-Dorsolateral: cognitive symptoms

-Orbitofrontal & connections to the amygdala: aggressive, impulsive symptoms

Brain Circuits Affected in Schizophrenia: correct answers -Dopamine Pathways
• explain the (+) & (-) symptoms seen in schizophrenia & psychosis

Dopamine Role in Psychosis correct answers -leading hypothesis
• psychosis & schizophrenia associated with dysfunction of neurotransmitter dopamine (DA)
➣Traditionally surplus of dopamine

Glutamate Role in Psychosis correct answers -primary excitatory neurotransmitter
-implicated in the overactivity of mesolimbic DA pathway in schizophrenia
-Glutamate hypoactivity may result in lost activation of the mesocortical dopamine pathway
leading to negative symptoms of schizophrenia

GABA is the primary _________ neurotransmitter correct answers inhibitory

Clinical domains of psychosis symptoms: Positive Symptoms correct answers -Hallucinations
-Delusions
-Thought disorder
-Hostility
-Excitability

Clinical domains of psychosis symptoms: Motor Symptoms correct answers -Motor delay
-Dyscoordination
-EPS, e.g.
• Parkinsonism
• Dyskinesia

, Clinical domains of psychosis symptoms: Affective Symptoms correct answers -Depression
-Anxiety
-Suicidality

Clinical domains of psychosis symptoms: Cognition correct answers -Attention
-Working memory
-Verbal memory
-Visual memory
-Executive functioning
-Processing speed
-Social conditioning

Clinical domains of psychosis symptoms: Negative Symptoms correct answers -Affective
flattening
-Alogia
-Anhedonia
-Amotivation
-Asociality

Hallucinations: correct answers -perceptual experiences in the absence of external stimuli
• Auditory
• Visual
• Tactile (feeling)
• Olfactory
• Gustatory (tasting)

Delusions: correct answers -fixed false, irrational beliefs

• Persecution: delusions related to being threatened, victimized, or spied on

• Reference: delusions related to receiving personal messages from television (tv), radio, or
actions of others

• Somatic: delusions related to the body, including illness or the presence of foreign objects (e.g.
Sometimes people believe there are objects in their bodies; for example they might think they are
infested with insects.)

• Grandeur: delusions related to beliefs of special abilities or powers

• Control: delusions that actions and thoughts are controlled by others

Thought Disorder: correct answers -impairment in the process of thinking & difficulty
organizing thoughts in a logical pattern
• incoherent speech
• loose associations

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