Exam (elaborations)

Virology Exam 2 Questions With Correct Answers

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Virology

Virology Exam 2 Questions With Correct Answers What type of virus is zika virus and how is it spread? - answerFlavivirus family; spread by mosquitoes which statement about polyadenylation of DNA viruses mRNAs is correct? a. it always occurs in the cytoplasm b. it occurs after cleavage of pre-...

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Uploaded on October 21, 2024
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virology exam 2 questions with correct answers

Institution Virology
Course Virology

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©SIRJOEL EXAM SOLUTIONS
10/7/2024 11:03AM

Virology Exam 2 Questions With Correct
Answers

What type of virus is zika virus and how is it spread? - answer✔Flavivirus family; spread by

mosquitoes

which statement about polyadenylation of DNA viruses mRNAs is correct?

a. it always occurs in the cytoplasm

b. it occurs after cleavage of pre-mRNA

c. polyA is added at the 5' end of pre-mRNA

d. is specified by a stretch of U residues in the template - answer✔b

adenovirus E1A protein stimulating the expression of adenovirus E2 protein which then

stimulates the expression of adenovirus IVa2 and L4 protein is an example of:

a. a negative auto regulatory loop

b. repression of gene expression

, ©SIRJOEL EXAM SOLUTIONS
10/7/2024 11:03AM

c. cascade regulation

d. dimerization - answer✔c

What serum samples do zika virus cross react with? - answer✔dengue, yellow fever, and CHIK

(makes prevalence of zika difficult to nail down)

Zika virus effect on pregnant woman: - answer✔may be passed from mother to child and cause

birth defect microcephaly (small head); studies suggest infection during 1st trimester leads to the

defects

List zika virus virology info. - genome, structure, entry mechanism, and transcription - answer✔-

genome: (+)ssRNA

-structure: enveloped icosahedral

-entry: receptor mediated endocytosis and low-pH induced fusion

-transcription: mRNA genome is immediately translated into 1 large polypeptide that is cleaved

by cellular & viral enzymes into individual proteins

Where was the largest outbreak of zika virus obsered? - answer✔brazil

, ©SIRJOEL EXAM SOLUTIONS
10/7/2024 11:03AM

How does zika virus enter the human population? - answer✔warm, urban environments with

standing pools of water attracts mosquitoes can lead to spread of virus (biting ppl), possible that

zika can be transmitted via sexual intercourse, blood transfusion, & in utero

cycle where mosquitos feed on monkeys that are infected and the virus goes back and forth

between monkey and mosquito - answer✔sylvatic cycle

cycle where mosquito finds a human to feed on and transmits a virus to a human - answer✔urban

cycle

Where does zika virus originate? - answer✔nonhuman primates in tropical rain forests

Zika is considered a _____ virus because it is transmitted via an insect vector -

answer✔Arthropod- Borne

an ___ is an arthropod-borne virus - answer✔arbovirus

What species of mosquito carries zika virus? - answer✔aedes aegypti, aedes albopictus, yellow

fever mosquito

two examples of an arthropod that can carry an arbovirus - answer✔mosquito, tick (sandflies,

aphids)

Describe a mosquito becoming a carrier of zika virus: - answer✔bite --> saliva numbing -->

intake an infected blood meal --> virus infects midgut cells --> virus spreads to hemolymph -->

virus reaches salivary glands & replicates

, ©SIRJOEL EXAM SOLUTIONS
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Describe mosquito transmitting zika virus to human: - answer✔infected mosquito bites human --

> injects saliva+zika --> zika enters human

How long does it take for a mosquito to become infectious with zika virus? - answer✔3-10 days

why are arbovirus infections a long process? - answer✔the virus needs to fully replicate in a

mosquito before it infects a human

Why do only female mosquitos bite humans? - answer✔they require a blood meal to produce

eggs

Zika virus symptoms, prevention, and treatment: - answer✔symptoms: fever, headache, red eyes,

skin rash, fatigue, joint pain

prevention: bug spray,cover water sources, insect screens

treatment: hydration

What virus is zika virus most similar to? - answer✔dengue virus

Most cases of zika virus are _____ - answer✔asymptomatic

During what year did US territories experience the most explosive zika virus outbreak? -

answer✔2016

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