A one-page summary Infection and Defence Notes on Post-Exposure Prophylaxis from a 4.00 GPA student. Notes are well-structured, easy to read, with tables and keyword colors. The details are summarized into short phrases in bullet points and fit into one page for spatial recall.
Hepatitis B virus Vaccinated: none
Previous vaccinated (not complete): hep B immune globulin followed by vaccine booster
Not vaccinated: hep B immune globulin followed by vaccine series
Hepatitis C virus No prophylaxis
HIV Any injury/mucocutaneous exposure: within 72 hrs for 28 days → Tenofovir + one prophylaxis (choose)
Varicella zoster virus Vaccinated: none
Not vaccinated: 2 cases
1) Healthy: vaccine within 5 days of exposure
2) Pregnant, neonate, immunocompromised: varicella zoster immune globulin asap
Rabies Vaccinated:
1) Last vaccine more than 6 months: 2 dose of vaccine
2) Last vaccine less than 6 months: 1 dose of vaccine
Not vaccinated: immediate vaccine followed by rabies immune globulin (category III)
Measles Vaccinated: none
*droplets & airborne Not vaccinated:
1) Healthy: vaccine within 3 days of exposure
2) Pregnant, immunocompromised: single dose of immune globulin
Invasive meningococcal Not vaccinated: begin antimicrobial chemoprophylaxis asap (no more than 14 days of exposure)
infection
*droplets
Pertussis Should be vaccinated every 10 years
*droplets
Tetanus Uncertain/Incomplete history of primary 3-dose series: tetanus toxoid-containing vaccine (Td, Tdap, TT)
Clean wounds → if most recent alrd >10 yrs: tetanus toxoid-containing vaccine (Td, Tdap, TT)
Dirty wounds → if most recent alrd >5 yrs: tetanus toxoid-containing vaccine (Td, Tdap, TT)
*add immune globulin if it is unclear the primary 3-dose series has been completed (except for clean wounds)
Tuberculosis Tuberculin skin test or IFN-y release assay within 8-12 weeks of exposure
*airborne If positive → treat w/ Isoniazid + vitamin B6 for 9 months
Diphtheria Any close contacts regardless of immunization status: Either Td or Tdap if no documentation of 3-dose primary series + one dose of drug
The benefits of buying summaries with Stuvia:
Guaranteed quality through customer reviews
Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.
Quick and easy check-out
You can quickly pay through credit card for the summaries. There is no membership needed.
Focus on what matters
Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!
Frequently asked questions
What do I get when I buy this document?
You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.
Satisfaction guarantee: how does it work?
Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.
Who am I buying these notes from?
Stuvia is a marketplace, so you are not buying this document from us, but from seller theanatomyholmes. Stuvia facilitates payment to the seller.
Will I be stuck with a subscription?
No, you only buy these notes for £4.51. You're not tied to anything after your purchase.
