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  3. University College London (UCL)
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  5. Medicine
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  7. Infection and Defence (CHMD1301)

Lecture notes

The All-In-One Notes Fungi
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Having a hard time remembering fungi? This All-In-One Fungi Summary from a 4.00 GPA medical student includes everything you need to know about fungi! It divides fungi into classes, color-coded, and gives detailed about the fungi and its key in a table format making it easy to read and spot out info...

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  • June 12, 2021
  • 3
  • 2020/2021
  • Lecture notes
  • Mr. taweegrit
  • All classes

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Fungi
Cutaneous Mycoses

Tinea (dermatophytes) ● Trichophyton ● Require keratin for growth
● Epidermophyton (does not infect hair) ● Itching, scaling skin patches or plaque
● Microsporum (does not infect nails) ● Spread centrifugal → red border w/ central clearing
● Tinea pedis: athlete’s foot
● Tinea corporis: body
● Tinea capitis: head
● Tinea cruris: jock itch
● Tinea unguium: nails
● Tinea faciei: face

Tinea (pityriasis) versicolor ● Malassezia furfur ● Spaghetti & meatball (budding yeasts & curved pseudohyphae)
● Colonizes normal skin
● Loves lipid, damage melanocyte → hypo/hyperpigmentation of skin


Subcutaneous Mycoses
Dermis, Subcutaneous, Bone (almost always traumatic injury)

Sporotrichosis* ● Sporothrix schenckii ● Dimorphic; hyphae & clusters of conidia
● Rose gardener’s disease: isolate from soil, plant → direct inoculation
● Papule at puncture site → secondary lesions along lymphatics
● Yeast form = lesions in infected tissue
● Mycelial form = culture plate
● Sporothrix ฉึกๆ หนามกุหลาบ

Chromoblastomycosis ● Fonsecaea pedrosoi ● Scaly, nodular, tumorous warts & crusty abscess esp. lower extremities
(Chromomycosis) ● Cladophialophora carrionii ● Limited to skin & subcutaneous tissue
● Phialophora verrucosa ● Trauma then conidia enters
● Exophiala jeanselmei ● Muriform cells (copper penny)

Mycetoma ● Madurella mycetomatis ● Branching septate hyphae
● Madurella grisea ● Madura foot
● Actinomadura madurae ● Triad
1) Localized swelling
2) Draining sinuses
3) Colored grains (aggregates of infecting organisms)
● Eumycetoma: eukaryotic fungi ‘true” (Madurella, Phialophora, Aspergillus, etc.)
● Actinomycetoma: gram-positive filamentous bacteria “atypical” (Actinomadura, Nocardia)
● Surgical incision

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