Lecture notes
Chapter 11: Glycolysis
Summary and outline for Glycolysis.
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Chapter 11: Glycolysis1) General Info
a) Irreversible
b) Occurs in cytoplasm of cells
c) Single molecule of glucose is converted to 2 molecules of 3-carbon pyruvate
w/ production of ATP
2) Anaerobic Glycolysis
a) Net yield of 2 ATP
b) Pyruvate converted to lactate catalyzed by lactate dehydrogenase
c) NADH is oxidized and NAD+ is used in the oxidation of glyceraldehyde 3-
phosphate allowing glycolysis to continue
3) Aerobic Glycolysis
a) Oxidative Phosphorylation
i) NADH donates electrons to electron transport chain reducing molecular
02 and H20. Regenerates NAD+ allowing glycolysis to continue
ii) Each molecule of NADH yields 2.5 molecules of ATP
b) Net yield of 5 ATP (7-2)
4) Phases
a) Energy Investment
i) Aka priming phase
ii) 2 molecules of ATP are invested to form fructose 1,6-bisphosphate
(intermediate)
iii) Fructose 1,6-bisphosphate is cleaved to form triose phosphates
(1) Glyceraldehyde-3-phosphate
(2) Dihydroxyacetone phosphate
iv) All intermediates are hexose sugars (6 carbons)
b) Payoff Phase
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