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Lecture notes

CELLULAR BIOCHEMISTRY
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Protein structure determination Exploring how structure underlies protein function. Specific protein cleavage. Sequencing of peptides – Edman degradation. Techniques used in protein structure elucidation, proteomics, and protein structure analysis. • Protein folding Folding of pro...

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  • June 27, 2023
  • 103
  • 2022/2023
  • Lecture notes
  • Dr. j. nyirenda (phd.)
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CHE 3111

CELLULAR BIOCHEMISTRY

Dr. J. Nyirenda (PhD.)
Room 226 Dept. of Chem.
January 2017

, Tentative teaching plan for CHE 3111

CHE 3111 Cellular CONTENT WEEKS LECTURER
Biochemistry
 Protein structure Determination 3 JN.

 Protein folding & examples of proteins 1 JN.

 Advanced enzyme catalysis 3 EF.

 Carbohydrate metabolism 2 BM.

 Lipid metabolism 2 BM.

 Metabolism of nitrogen 4 CM.

,• 4 Weeks beginning 28th October 2013
• Topics (hopefully to be covered within 4 weeks)
• Protein structure determination
Exploring how structure underlies protein function.
Specific protein cleavage. Sequencing of peptides –
Edman degradation. Techniques used in protein structure
elucidation, proteomics and protein structure analysis.
• Protein folding
Folding of proteins in biological systems; Importance of
correct folding, Heat shock proteins, Molecular
chaperones. Protein homologies.
• Examples of proteins
Myoglobin and Haemoglobin as examples of proteins.
Interaction proteins-proteins interactions small ligands

, Mode of Delivery:
Lectures: 3 hours per week
Tutorials: 1 hour per week ( Thur or Fri - 15hrs)
Laboratory practical: 3- hour session per week (Thur or Fri)

Assessment:
Continuous Assessment (CA): 40 %
Assignments/quizzes 5 %
Laboratory 15 %
Tests 20 %

Written Final Examination: 60 %
Total 100 %

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