BOC Fixation quizzes and VERIFIED SOLUTIONS

BOC Fixation An example of an additive fixative is one that contains: A. Picric Acid B. Acetic Acid C. Ethyl Alcohol D. Acetone ANSWERS:- Picric Acid When compared with tissue fixed in formalin, tissue fixed in zinc-formalin will show: A. Better ultrastructural preservation B. Decreased immunoreactivity C. Increased enzyme activity D. Superior nuclear detail ANSWERS:- Superior nuclear detail Microscopic examination of an H&E stained section fixed in formalin shows marked nuclear bubbling. One most often sees this artifact if the specimen is processed following: A. Incomplete fixation B. Prolonged fixation C. Microwave fixation D. Frozen Sectioning ANSWERS:- Incomplete fixation Microscopic evaluation of H&E stained sections from a surgically removed small bowel specimen shows an absence of much of the epithelium in otherwise normal tissue. This is most likely resulted from: A. Mechanical trauma B. Delayed fixation C. Ulceration D. Poor choice of fixative ANSWERS:- Delayed fixation A specimen of kidney must be shipped to another city for immunofluorescence studies. The specimen should be placed in : A. Saline B. Michel solution C. Buffered formalin D. Orth ANSWERS:- Michel solution A certain project requires a fixative that contains acetic acid yet stabilizes erythrocyte membranes. One fixative that could be used is: A. Zenker B. Bouin C. Gendre D. Hollande ANSWERS:- Hollande