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ABGC Boards Prenatal Exam Study Set With 100% Correct And Verified Answers 2024
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ABGC Boards Prenatal Exam Study Set With 100% Correct And Verified Answers 2024
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ABGC Boards Prenatal Exam Study Set With 100% Correct And Verified Answers2024
T21 Risk by Maternal Age - Correct Answer-Age-------------------------------Risk
30 --------------------------------1/952 (.1%)
35 --------------------------------1/385 (.3%)
37 --------------------------------1/227 (.4%)
40 --------------------------------1/106 (.9%)
43 --------------------------------1/50 (3.1%)
Risk of Any Chrom Abnl by Maternal Age - Correct Answer-Age--------------------------------
Risk
30---------------------------------1/384 (0.3%)
35---------------------------------1/202 (0.5%)
37---------------------------------1/129 (0.8%)
40---------------------------------1/65 (1.6%)
43---------------------------------1/32 (3.1%)
Maternal Serum Quad Screen - Correct Answer-Measurement of biochemical analytes in maternal serum to provide adjusted risk for certain conditions. Performed during second trimester typically 14-21 weeks
SLO vs XL ichthyosis,
SLO has pre and postnatal growth restrictions - Correct Answer-Differentials for extremely low uE3 on QUAD screen and how can you differentiate
Non-disjunction in Meiosis I - Correct Answer-What is the most common cause of aneuploidy
Quad screen conditions - Correct Answer--Open Neural tube defects
- Down Syndrome
- Trisomy 18
Quad screen analytes - Correct Answer--AFP (alpha-fetoprotein) -hCG (human chorionic gonadotrophin): -uE3 (unconjugated estriol): - Inhibin Factors to take into account for Quad Screen - Correct Answer-Gestational Age: As this changes so does expected values of each analyte
Weight: as maternal weight increases so does blood volume. Dilutes analytes
Race: Different ethnic backgrounds can affected expected levels
- i.e. African American ancestry tend to have higher AFP levels
-Diabetic status: insulin dependent diabetics tend to have lower AFP
Effects of inaccurate dating for Quad Screen - Correct Answer--Overestimate (believe pregnancy is further along) can lead to false positive for Down syndrome. (Overestimate
brings you down)
- Underestimate (reported to be earlier than it is) leads to false positive for NTD. London
(The under is the tubes)
- Generally use first trimester ultrasound for dating rather than LMP
IgM (Most recent)
IgG (It is gone) - Correct Answer-You see IgM but not IgG is this more concerning for recent infections due to maternal infection.
Memory device
Estriol and hCG low but AFP high early
All low: Late - Correct Answer-Patterns for recent and older fetal demise
Trends of Analytes in Second Trimester - Correct Answer-Analyte Trend
hCG Decreases as GA increases
Inhibin Remains Stable
uE3 Increases with GA
AFP increases with GA
Positive Quad screen pattern Increased risk for Down Syndrome - Correct Answer-HI (Increased) LO (Decreased)
H: hCG
I: Inhibin
L: estriol
O: AFP Quad screen positive T18 increased risk - Correct Answer-AFP: Low
hCG: Low
uE3: Low
DIA: N/A
Pattern of Quad screen with abnormal placental functioning - Correct Answer-AFP: HI
hCG: High
uE3: Low
Inhibin: High
First Trimester Screening - Correct Answer-Maternal serum analytes and ultrasound are
used to adjust a woman's a priori risk for aneuploidy. Performed in 1st trimester usually between 11-13 weeks
First Trimester Screening Analytes - Correct Answer-Free Beta-hCG
PAPP-A
AFP
Analytes are measures and then adjusted for gestational age, maternal weight and race
Measured in MoM- multiples of median
First Trimester Screen Ultrasound Components - Correct Answer-Crown to Rump length measurement
Nuchal translucency
Nasal Bone
Advantages of First Tri Screening over Quad - Correct Answer-Increased sensitivity for T21 and T18
Includes T13
Risk assessment earlier
Eliminates incorrect dating issue
Nuchal translucency - Correct Answer-a collection of fluid that extends behind the fetal neck and along the spine in the first trimester
Increased NT - Correct Answer-Greater than 95th percentile in size
Increased NT associated with what genetic conditions? - Correct Answer-- Down syndrome
- Trisomy 18
- Trisomy 13
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