Biology A2 level 3.3 respiration. These notes were formulated using class notes, the WJEC study guide and past papers. These notes helped me to achieve an A* at A level biology!
● Adenosine triphosphate
● Nucleotide
● Universal energy carrier (used for all reactions in all organisms)
● Small and water soluble
● Releases energy in small quantities (30.6kj per mol)
○ High energy bond between 2nd and 3rd phosphate group (terminal bond) is broken
○ Hydrolysis reaction
○ Catalysed by ATPase
● ATP is reformed by phosphorylation
○ Pi + ADP ⇾ ATP
○ Condensation reaction
● Energy used for;
○ Protein synthesis
○ Muscle contraction
○ Active transport
○ Respiration
○ Mitosis
● Types of phosphorylation
○ Oxidative phosphorylation - Pi is added to ADP using energy from electron loss
○ Photophosphorylation - energy that powers ETC in chloroplasts comes from light
○ Substrate level phosphorylation - Pi groups are transferred from donor molecules
Mitochondria
● 0.5 - 1.0μm in diameter
● Outer membrane contains transport proteins - transport of pyruvate
● More active mitochondria have more cristae (membrane folds) for more SA:vol
● Inner membrane contain ETC and ATP synthase
● Intermembrane space maximises hydrogen gradient
● Matrix contains suitable enzymes and pH for krebs cycle
● Microscope shape changes depending on cross-section
, Overview of respiration
Aerobic respiration
● Complete breakdown of glucose
● Releases relatively large amount of energy (32-38 ATP by oxidative phosphorylation)
● O2 is the final electron acceptor
Anaerobic respiration
● In muscles
○ Glucose ⇾ lactic acid
○ C6H12O6 ⇾ 2C3H6O3
● In yeast
○ Glucose ⇾ ethanol + carbon dioxide
○ C6H12O6 ⇾ 2C2H5OH + 2CO2
● Incomplete breakdown of glucose
● Releases relatively little energy as ATP by substrate level phosphorylation
● Occurs in absence of oxygen e.g. vigorous exercise
Aerobic respiration
Glycolysis
● Cytoplasm
● Does not require O2
● Net gain +2 ATP
1. Phosphorylation of glucose
a. Glucose is phosphorylated (6C + 2x Pi) ⇾
hexose bisphosphate
i. 2 ATP are hydrolysed to obtain
phosphates - 2 ATP ⇾ 2ADP + 2Pi
2. Splitting of phosphorylated glucose
a. Hexose bisphosphate more reactive
(lowers Ea for reaction) splits to 2x TP (3C)
3. Oxidation of 2x TP to form 2x Pyruvate
a. Dehydrogenation (removal of H atoms
catalysed by dehydrogenase enzymes)
i. 2 NAD + 2 H ⇾ 2 reduced NAD
The benefits of buying summaries with Stuvia:
Guaranteed quality through customer reviews
Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.
Quick and easy check-out
You can quickly pay through credit card for the summaries. There is no membership needed.
Focus on what matters
Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!
Frequently asked questions
What do I get when I buy this document?
You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.
Satisfaction guarantee: how does it work?
Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.
Who am I buying these notes from?
Stuvia is a marketplace, so you are not buying this document from us, but from seller atwellkate. Stuvia facilitates payment to the seller.
Will I be stuck with a subscription?
No, you only buy these notes for £4.99. You're not tied to anything after your purchase.