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PNB 2274 UCONN Exam 2 Tanner Questions And Answers Rated A+
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PNB 2274 UCONN Exam 2 Tanner Questions And Answers Rated A+ Principles Electrostatic Attraction ANS - charge attraction - positively charged ions will be attracted to negatively charged ions Principles Chemical (diffusional) Gradients ANS - when a membrane is selectively permeable positively...

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  • October 9, 2024
  • 10
  • 2024/2025
  • Exam (elaborations)
  • Questions & answers

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  • pnb 2274 uconn exam 2
  • pnb 2274 uconn exam 2 tanner questions and answers
  • pnb 2274 uconn exam 2 tanner

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  • PNB 2274 UCONN

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PNB 2274 UCONN Exam 2 Tanner Questions And
Answers Rated A+
Principles Electrostatic Attraction ANS - charge attraction
- positively charged ions will be attracted to negatively charged ions



Principles Chemical (diffusional) Gradients ANS - when a membrane is selectively permeable
positively charged ions will flow to the one side making the other side negative due to leak channels.
- making one side harder to diffuse with the outside of the cell because it is attracted to the more
charged side.



Relate diffusional and electrical gradients to behavior of ions ANS - individually ions will be
attracted to one another if opposite charges
- A Nernst equilibrium forms when there is a balance of ions between the electrostatic attraction and
diffusional gradient of the ions
- no ion wants to flow either in or out of the cell.


Principles of Equilibrium ANS membrane potential at which an ion's net flux is 0



Nernst Equation ANS -used for only one ion at a time
-Ex = equilibrium potential
-determines the electrical potential (voltage) at which diffusion flow of an ion one way is balanced by
electrostatic attraction in the other



What effect Equilibrium Potential ( Ex) ? ANS - temperature
- Concentration of ion



Mammalian ion concentrations and Nernst Potentials ANS Ek = -90, ECl = -70, ENa = +60, ECa
= +130
- these values can change based on condition

, Goldman- Hodgkin- Katz Equation ANS -the membrane is permeable to more than 1 ion at rest
-Vm = membrane potential when net flux of all other ions together is 0
-membrane have one Vm value; it is the average Ex values for each ion
- ** permeability matters



Goldman Equation: Multiple ion Case ANS Vm is somewhere between the largest Ex and
smallest Ex.



Goldman Equation: One ion Case ANS - GHK reduces to Nernst

- Vm approximates Ex of the most permeant ion


Depolarization ANS - Changing membrane potential to be more positive (MORE +)



Hyperpolarization ANS - Changing membrane potential to be more negative (MORE -)



Repolarization ANS Returning membrane potential

towards rest potential


Dendrite ANS - input signal
-receive incoming signals
-passive, graded synaptic potentials



Axon ANS -output signal
-an all-or-nothing action potential



Action Potentials ANS - Active
- no decrement with distance or time
- "All or none"

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