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Test Bank Solution Manual for Blood Banking Reagents Already Passed £6.95
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Test Bank Solution Manual for Blood Banking Reagents Already Passed

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Test Bank Solution Manual for Blood Banking Reagents Already Passed Reagent RBCs - Answers commercially prepared known source of Ag Patient or Donor RBCs - Answers usually an unknown source of Ag RBCs are tessted w/ commercial antisera to determine Ag ID Reagent antisera - Answers commercial...

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Document information

  • October 10, 2024
  • 5
  • 2024/2025
  • Exam (elaborations)
  • Questions & answers

Subjects

  • blood bank reagents

Written for

  • Blood Bank
  • Blood Bank

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TutorJosh

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Test Bank Solution Manual for Blood Banking Reagents Already Passed

Reagent RBCs - Answers commercially prepared

known source of Ag

Patient or Donor RBCs - Answers usually an unknown source of Ag

RBCs are tessted w/ commercial antisera to determine Ag ID

Reagent antisera - Answers commercially prepared

known source of Ab

Pt or Donor Serum or Plasma - Answers usually unknown

serum or plasma is tested w/ commerical RBCs to determine ID of Ab or Abs

ABO/D typing (forward grouping) - Answers Detects A, B, and D Ags

Source of Ag: pt RBC

Source Ab: Commercial

ABO serum testing (reverse grouping) - Answers Detects ABO Abs

Source of Ag: reverse grouping cells (A1 and B)

Source of Ab: pts serum/plasma

Ab Screen - Answers detects Abs with specificity to RBC Ags

Source of Ag: screening cells

Source of Ab: pts serum/plasma

Ab ID - Answers ID specificity of RBC Abs

Source of Ag: Panel cells

Source of Ab: pt serum/plasma

Crossmatch - Answers determines serologic compatibility btwn donor and pt before transfusion

Source of Ag: Donor RBCs

Source of Ab: pt serum or plasma

4 Basic Categories of Reagents - Answers RBCs with known Ags

, Antisera w/ known Abs

Antiglobulin reagents: anti-IgG and or complement

Potentiators to enhance Abs

Reagent Regulation - Answers FDA's criteria:

Reagents must meet minimum standards before being licensed

Specificity: recognition of the antigenic determinant and its corresponding Ab

Potency: strength of the reaxn

Polyclonal Abs - Answers Made from several different clones of B cells that secrete antibodies of
different specificities

Recognize multiple epitopes

Example: antihuman globulin (AHG)

Monoclonal antibodies - Answers Made from single clones of B cells that secrete antibodies of the same
specificity

Use hybridoma- a hybrid cell formed by the fusion of a myeloma cell and an antibody-producing cell; it is
used in the production of monoclonal antibodies.

technology

Recognize a single epitope

Examples: anti-A, anti-c, and anti-IgG antibodies

ABO Typing - Answers Anti-A and anti-B reagents are used to determine the ABO blood type



Both antisera are directed toward specific antigens on the patient's RBCs

Anti-A: directed toward A antigen

Anti-B: directed toward B antigen

ABO Typing (cont'd) - Answers Reagents are formulated to give a strong reaction (3+ to 4+)



Testing is performed in the immediate-spin (IS) phase

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