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Bioinformatics Chapter 6 Exam Questions with Verified Answers Latest Update (Graded A+) £5.72
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Bioinformatics Chapter 6 Exam Questions with Verified Answers Latest Update (Graded A+)
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Bioinformatics Chapter 6 Exam Questions with Verified Answers Latest Update (Graded A+) bioinformatics - Answers computational biology; application of computer programs and using biological data to look at patterns and make predictions structural similarity - Answers implies functional similarity...

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  • October 29, 2024
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  • 2024/2025
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Bioinformatics Chapter 6 Exam Questions with Verified Answers Latest Update (Graded A+)

bioinformatics - Answers computational biology; application of computer programs and using biological
data to look at patterns and make predictions

structural similarity - Answers implies functional similarity regardless of species from which protein
came

homolog - Answers homology between 2 sequences is based on % identity and % similarity; 2 sequences
that are very similar

paralog - Answers homologous genes in single species resulting from a gene duplication event but may
have different biological functions

ortholog - Answers homologous genes in different species originating from common ancestor; have very
similar biological functions

how to determine if two proteins are homologous - Answers compare sequence and structure

sequence alignment - Answers line up two sequences in different ways to determine # of amino acids
that match

gaps - Answers space in one of the sequences that give more amino acids that line up

BLAST website - Answers can align nucleotides as well; we want Protein BLAST; can search through
genome databases to find sequence that will give information about function

shuffling - Answers approach to authenticate alignment and rule out that alignment has happened
randomly; takes first sequence and puts in every possible position and compares all of these alignments
with the second sequence; gives best alignment score and compares to all other alignments

Blosum-62 Matrix - Answers provides matrix for types of substitutions that occur between homologs;
large positive score means substitution occurs frequently - homologous

conservative substitution - Answers can have positive alignment scores for substitutions; similar amino
acid side chains with similar properties are considered conservative substitutions

repeated shuffling vs. alignment with Blosum 62 - Answers will get a higher alignment score using
Blosum 62

E-value - Answers how likely you could get that alignment randomly; want a smaller E-value which
means alignment is less likely to be random; want score LARGER than E-value

identities - Answers how many amino acids are same

positives - Answers same amino acids or similar amino acids (indicated by a +)

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