Mechanisms of pathology

Aston University, Birmingham (Aston)

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innate immunity
  • innate immunity

  • Lecture notes • 17 pages • 2024
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  • preview:First lines of defence • Barriers-skin, mucosal surfaces (epithelial cells) • Prevent entry of pathogens • Mechanical • Chemical • Microbiological • We have got a multi layered defense. • the first lines of defense are always ready for action these are barriers, these are our skin, these are mucosal surfaces, and these prevent the entry of pathogens. • We have barriers that are mechanical, chemical and microbiological. • For mechanical barriers you can se...
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Autoimmunity
  • Autoimmunity

  • Lecture notes • 18 pages • 2024
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  • in depth highly detailed immunology notes. includes extra reading as-well as the basic lecture material
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Antigen recognition by T cells
  • Antigen recognition by T cells

  • Lecture notes • 15 pages • 2024
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  • pre-made in depth immunology notes from an aston university student for bioscience students!
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principles of adaptive immunity
  • principles of adaptive immunity

  • Lecture notes • 11 pages • 2024
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  • • Adaptive immunity is the third line of defence. • It happens after the physical barriers such as tears, skin mucous and stomach acid. • This is followed by innate immunity which is the immune system that is present from birth, this includes soluble mediators such as complement and cytokines in the blood. And also includes a number of cell types that it can immediately recognise and attack pathogens after they have infected our body. • Adaptive immunity • Requires different types ...
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hypersensitivity
  • hypersensitivity

  • Lecture notes • 17 pages • 2024
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  • immunology notes that are in depth. includes extra reading
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Antibody structure and B cells
  • Antibody structure and B cells

  • Lecture notes • 9 pages • 2024
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  • preview:• also known as immunoglobulins (Ig) • Ab are the targeted weapons of the adaptive immune system • clear extracellular pathogens and neutralise toxins • produced by activated, effector B lymphocytes (plasma cells) • circulate in plasma and lymph and are found at mucosal surfaces • specific – bind only a single antigen (Ag) • the antibody repertoire is very large – 109-1016 unique molecules • Antibodies are able to clear extracellular pathogens and neutralize t...
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Defence against infection
  • Defence against infection

  • Lecture notes • 15 pages • 2024
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  • 1st class immunology notes providing in depth notes
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failures of defence
  • failures of defence

  • Lecture notes • 16 pages • 2024
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  • immunology notes that are in depth
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Tumour immunology
  • Tumour immunology

  • Lecture notes • 8 pages • 2024
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  • in depth immunology notes, made using synchronous, asynchronous and extra reading material
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