Synthesis routes Study guides, Revision notes & Summaries

NRNP 6566 Mid-term Study Guide Week 1 to 5 Week 1 1. Describe the cytochrome P450 system. Describe how inducers and inhibitors affect the cytochrome system and how that affects the half-life of medications. Cytochromes P450 (CYPs) are a superfamily of enzymes containing heme as a cofactor that function as monooxygenases. In mammals, these proteins oxidize steroids, fatty acids, and xenobiotics, and are important for the clearance of various compounds, as well as for hormone synthesis and br...

PHARMACOLO MSN 571 Question Bank Pharm 2022- United State University 1. Which instructions should be included in the plan of care for a patient who is prescribed ferrous sulfate? a. Iron compounds are not taken orally b. Iron does not absorb c. Iron should only be taken at night d. Antacids should not be taken with iron 2. Which is the most common type of anemia? a. Iron deficiency b. Sickle cell anemia c. Folic acid deficiency d. B12 deficiency 3. Which antibiotic class disrupts fol...

NRNP 6566 WK1-5 Midterm EXAM ( A+ GRADED 100% VERIFIED) LATEST 2022 Describe cytochrome p450 system - ANS Cytochrome p450 system is a series of enzymes used to metabolize medications Inhibitors - ANS block metabolic activity from one or more CYP450 enzymes Inducers - ANS increase CYP450 enzyme activity by increasing enzyme synthesis Describe effect on low and high albumin levels on active drug levels especially for drugs that are highly protein bound - ANS Albumin is the plasma pro...

Demonstration and Research Pest Control Latest Update Graded A+ Federal Insecticide Fungicide and Rodenticide Act FIFRA "any substance or mixture of substances intended for preventing, destroying, repelling, or mitigating and pest" Pesticide "any substance or mixture of substances intended for use as a plant regulator, defoliant, or desiccant." Pesticide Pesticides that are generally more acutely toxic and inhibit a vital physiological process. Broad spectrum Broad spectru...

Resources LESSON 1: Cell cycle g1- increase in size s- dna replicated g2- cell enlarge and ready to divide m phase- 2 hours mitosis 4 stages, prophase, metaphase, anaphase, telophase -chemo targets certain points in the process apoptosis programmed cell death hematopoiesis formation of blood cells & how cells differentiate -myeloid: pre cells mature into RBCs, platelets and WBCs -lymphoid: pre cells- mature into WBCS Principles of Biotherapy: p51-95 immunol...

Penicillin G *** - ANSWER - First PCN given PO and IM - PO only about 1/3 of dose is absorbed - IM and IV are most effective (to get therapeutic serum level) (IM is painful) - primarily bactericidal Penicillin V *** - ANSWER - next type produced - 2/3 absorbed by GI tract, less patent than PCN G - It is effective against mild - moderate infections, including anthrax PCNS (structure) - ANSWER - beta-lactam antibiotics. - beta-lactam structure interferes with bacterial cell wall synth...

Rasmussen Pathophysiology Final Exam Questions and Answers Already Passed Define Pathophysiology The study of the changes of normal mechanical, physical, and biochemical functions, either caused by disease or resulting from an abnormal syndrome. What does the study of pathophysiology include? Contains etiology, which is the reason for the phenomena, pathogenesis, which is the development of a disease, clinical manifestations, which is the manifestation of the disease in signs, sympt...

Describe cytochrome p450 system Cytochrome p450 system is a series of enzymes used to metabolize medications Inhibitors block metabolic activity from one or more CYP450 enzymes Inducers increase CYP450 enzyme activity by increasing enzyme synthesis Describe effect on low and high albumin levels on active drug levels especially for drugs that are highly protein bound Albumin is the plasma protein with the greatest capacity for binding drugs. Binding plasma proteins affe...

Describe cytochrome p450 system - correct answer Cytochrome p450 system is a series of enzymes used to metabolize medications Inhibitors - correct answer block metabolic activity from one or more CYP450 enzymes Inducers - correct answer increase CYP450 enzyme activity by increasing enzyme synthesis Describe effect on low and high albumin levels on active drug levels especially for drugs that are highly protein bound - correct answer Albumin is the plasma protein with the greates...

Describe cytochrome p450 system - CORRECT ANS Cytochrome p450 system is a series of enzymes used to metabolize medications Inhibitors - CORRECT ANS block metabolic activity from one or more CYP450 enzymes Inducers - CORRECT ANS increase CYP450 enzyme activity by increasing enzyme synthesis Describe effect on low and high albumin levels on active drug levels especially for drugs that are highly protein bound - CORRECT ANS Albumin is the plasma protein with the greatest capacity for b...