Checkpoint inhibitors - Study guides, Revision notes & Summaries

Summary that includes all lectures given by Schuringa, Van Vught, Kruyt and de Jong.The topics of the lectures are: carcinogenesis, cancer stem cells, the role of oncogenes and tumor suppressor genes, the large variety of subtypes within hematological and solid tumors, the signaling pathways active in different tumor types, genetic regulation of these molecular pathways (epigenetics, miRNA), DNA damage response, the tumormicroenvironment , the process of metastasis, tumor immunology, therapeutic...

4 Key Cell Cycle Checkpoint

Checkpoint inhibitors to treat cancer

Hematologic cancer (blood cancer) - Answer- -cancer that begins in bone marrow or immune system cells. -Ex: leukemia, lymphoma, multiple myeloma Leukemia - Answer- cancer starts in blood-forming tissues like bone marrow -causes lots of abnormal blood cells to be produced and enter bloodstream Lymphoma - Answer- -cancer that begins in immune system (WBC=lymphocytes) -hodgkin and non-hodgkins -B lymphocytes (B cells) - make antibodies (bacteria and viruses, most common lymphoma -T lymph...

Chemo Certification Renewal Exam With 100% Correct Answers 2023 The standard states that gowns must: A. be disposable B. not have any closures or seams that HDs can pass through C. be changed every shift if there are no specific manufacturer recommendations D. both a & b - Correct answer-D. both a & b Which of the following is a general recommendation regarding the administration of hazardous drugs? A. A NIOSH-approved respirator is required for all intravenous administration. B. Reuse...

Mitochondrial DNA is _______, ________-stranded, with NO _______ nor _______ circular, double-stranded, NO telomeres or histone proteins Rough ER Smooth ER protein synthesis (ribosomes) lipid synthesis Golgi Apparatus where cellular modification occurs (in vesicles) Microtubules: 3 Types Cilia Flagella Centrioles Intermediate filaments function *Allow cell to withstand ________ forces cell-cell adhesion and cell integrity mechanical forces ...

BIOL 133 EXAM 2 CHAPTER 7 TO 11 – QUESTION AND ANSWERS BIOL 133 EXAM 2 CHAPTER 7 TO 11 – QUESTION AND ANSWERS Exam 2-Chapters 7-11 Return to Assessment List Part 1 of 1 - 100.0 Points Question 1 of 40 2.5 Points If rubisco does not function properly, what process would be affected? • A. ability to reduce NADP+ • B. ability to absorb photons • C. ability to fix carbon • D. ability to split water Feedback: Correct Question 2 of 40 2.5 Po...

BIOL 133 EXAM 2 CHAPTER 7 TO 11 – QUESTION AND ANSWERS| 2022 LATEST UPDATE | GRADED A+BIOL 133 EXAM 2 CHAPTER 7 TO 11 – QUESTION AND ANSWERS Exam 2-Chapters 7-11 Return to Assessment List Part 1 of 1 - 100.0 Points Question 1 of 40 2.5 Points If rubisco does not function properly, what process would be affected? • A. ability to reduce NADP+ • B. ability to absorb photons • C. ability to fix carbon • D. ability to split water Feedback: Co...

Chapter 1: PATHOPHYSIOLOGY 370 FINAL EXAM STUDY GUIDE 1. Etiology: study of causes or reasons for a particular injury. Idiopathic (unknown) vs Iatrogenic (unintended/unwanted medical treatment ). Risk Factor: a factor that increases the likelihood of disease. 2. Pathogenesis: development or evolution of disease from initial stimulus to ultimate expression of manifestations of the disease. 3. Clinical Manifestations: Signs (objective) vs Symptoms (subjective). 4. Stages and Clinical Course: Laten...

BIO133 Exam #2 Chapters 7-11 Week #8 taken 25 September 2020 87.08% Part 1 of 1 - 87.08/ 100.0 Points Question 1 of 40 2.5/ 2.5 Points Damaged DNA can potentially be repaired during which checkpoint. Select all that apply. A. G1 B. S C. G2 D. G0 Feedback: Correct Question 2 of 40 2.5/ 2.5 Points Teeth can have a biofilm formed on the surface. Cell signaling will A. cause uncontrolled cell division B. cause increase saliva production C. cause apoptosis D. increase cell quantity Feedback: Correct!...