Bcl 2 - Study guides, Revision notes & Summaries

NBME PATHOLOGY EXAM WITH LATEST VERIFIED QUESTIONS AND 100% CORRECT ANSWERS GRADED A+ Apoptosis: - ANS-Programmed cell death. REQUIRES ATP. Can occur via the intrinsic or extrinsic pathways, both of which involve activation of cytosolic caspases which mediate cellular breakdown. ***Unlike necrosis, apoptosis does not involve significant inflammation. Involves eosinophilic cytoplasm, cell shrinkage, pyknosis and basophilia, membrane blebbing and karyorrhexis, and formation of apoptot...

define cell necrosis (Ans- - irreversible injury - rapid plasma membrane structure loss - organelle swelling - mitochondrial dysfunction what happens in cell necrosis (Ans- - cell membrane is ruptured - leakage of cell contents - ATP is lost - organelles swell - severe mitochondrial damage - local inflammation define apoptosis (Ans- programmed cell death; not associated with inflammation list the three mechanisms of apoptosis (Ans- 1. apoptosis triggered by inter...

MMSC 490 Final Exam Questions with Correct Answers Humans possess about .............. different cell types. 100 200 500 1,000 - Answer-200 In adult organisms, cell death must be balanced by cell growth. differentiation. renewal. migration. - Answer-renewal The distinct series of changes that characterizes programmed cell death is called necrosis. apoptosis. sepsis. execution. - Answer-apoptosis Cells that die as the result of acute injury undergo lysis. sepsis. apoptosi...

MMSC490 Final Exam Questions with 100% Answers Humans possess about .............. different cell types. 100 200 500 1,000 - Answer️️ -200 In adult organisms, cell death must be balanced by cell growth. differentiation. renewal. migration. - Answer️️ -renewal The distinct series of changes that characterizes programmed cell death is called necrosis. apoptosis. sepsis. execution. - Answer️️ -apoptosis Cells that die as the result of acute injury undergo lysis. sepsis...

19S - regulatory particle of proteasome 2 Categories of Epigenetics - DNA methylatioin and histone modification 20S - core particle of proteasome 26S proteasome - inhibited in sporadic parkinsonism 3 groups of Bcl-2 family proteins - 1. Group I - Anti-apoptitic 2. Group II - Inducers 3. Group III - Potentiate 3 key molecules of apoptosis - 1. Bcl-2 family proteins 2. Apaf-1 3. caspases 3 metabolic pathways that regulate aging - 1. Dietary restrictions 2. Insulin/Insulin-like Growth Fa...

MMSC 490 Final Exam Questions with Correct Answers Humans possess about .............. different cell types. 100 200 500 1,000 - Answer-200 In adult organisms, cell death must be balanced by cell growth. differentiation. renewal. migration. - Answer-renewal The distinct series of changes that characterizes programmed cell death is called necrosis. apoptosis. sepsis. execution. - Answer-apoptosis Cells that die as the result of acute injury undergo lysis. sepsis. apoptosis. ...

CELL BIO EXAM 3 QUESTIONS & ANSWERS what are the 6 major types of cell death - Answer-1. necrosis 2. apoptosis 3. autophagy 4. mitotic catastrophe 5. senescence 6. ferroptosis what are the two major reasons that cell-cell death is good - Answer-1. maximize killing cancer cells 2. to prevent genomic instability and malignant transformation due to damage in a normal cell (especially dsDNA breaks) This uncontrolled form of cell death is morphologically characterized by cell membrane swel...

TBI (traumatic brain injury) scale - Answer- 3-15, <8 = coma 3-8: Severe 9-12: Moderate 13-15: Mild (Behavior should elicit response, each response has a point value for eye opening, verbal, and motor responses) Intraparenchymal hemorrhage is often caused by... - Answer- Hypertension Septum pellucidum is located... - Answer- Inferior to corpus callous, separates lateral ventricles Which cell organelle contributes to the phospholipid content of brain white matter? - Answer- Pe...

MMSC490 Questions Final chp.18 Exam Questions with Correct Answers The Bcl-2 family of proteins is divided into three functional groups that contain and share as many as four Bcl-2 homology domains (BH domains). Which of the following is common to all members of the Bcl-2 family? a. BH1 b. BH2 c. BH3 d. BH4 - Answer ️️ -BH3 which of the following stem cells have the capacity to give rise to all the differentiated cell types of adult organisms? - Answer ️️ -embryonic stem cells ...

The Bcl-2 family of proteins is divided into three functional groups that contain and share as many as four Bcl-2 homology domains (BH domains). Which of the following is common to all members of the Bcl-2 family? a. BH1 b. BH2 c. BH3 d. BH4 - ️️BH3 which of the following stem cells have the capacity to give rise to all the differentiated cell types of adult organisms? - ️️embryonic stem cells Murine embryonic stem cells are grown in the presence of a growth factor. What g...

Bcl-2 ____ cell death - inhibits Bad, Bax and Bid _______ cell death - promote pro-apoptotic complexes insert into - outer mitochondrial membrane cytochrome c is usually in - the inner membrane space cytochrome c - moves electrons in electron transport chain cytochrome c binds ______ and _________ to form the ____________ - adaptor, caspases, apoptosome caspases - special kinds of proteases involved in cell death