Cancer hallmarks - Study guides, Revision notes & Summaries
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GMS 6540 exam with complete answers
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Ras signaling 
- GTPase 
- promotes growth and proliferation 
- mutated in 20-30% of all cancers 
- point mutations are most common 
 
 
 
G12V mutation 
- blocks GAP binding 
- locks RAS in active state, promoting proliferation 
 
 
 
Q61K mutation 
- raises activation energy of GTP hydrolysis 
- blocking hydrolysis, keeping RAS active 
 
 
 
Hallmarks of cancer 
1) self-sufficiency in growth signals 
2) insensitivity to anti-growth signals 
3) unstable DNA 
4) metastasis 
5) evasion of apoptos...
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GMS 6552 Exam 2 Questions and Answers 100% Correct!
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Oncogene - ANSWER-A gene that causes or contributes to the development of cancer 
 
Hallmarks of Cancer - ANSWER-Sustaining proliferative signaling 
Evading growth suppressors 
Activating invasion and metastasis 
Enabling replicative immortality 
Inducing angiogenesis 
Resisting cell death 
 
In vivo oncogenic evidence - ANSWER-Cause cancer when activated in a transgenic animal 
Render nontumorigenic cells tumorigenic 
Knock down or knock out in tumorigenic cells renders the cells nontumorigenic...
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GMS 6552 Exam 2 Questions and Answers 100% Correct!!
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Oncogene - ANSWER-A gene that causes or contributes to the development of cancer 
 
Hallmarks of Cancer - ANSWER-Sustaining proliferative signaling 
Evading growth suppressors 
Activating invasion and metastasis 
Enabling replicative immortality 
Inducing angiogenesis 
Resisting cell death 
 
In vivo oncogenic evidence - ANSWER-Cause cancer when activated in a transgenic animal 
Render nontumorigenic cells tumorigenic 
Knock down or knock out in tumorigenic cells renders the cells nontumorigenic...
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CANCER BIOLOGY LECTURE 3 CELLULAR HALLMARKS OF CANCER REVIEW EXAM Q & A
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CANCER BIOLOGY LECTURE 3 CELLULAR HALLMARKS OF CANCER REVIEW EXAM Q & ACANCER BIOLOGY LECTURE 3 CELLULAR HALLMARKS OF CANCER REVIEW EXACANCER BIOLOGY LECTURE 3 CELLULAR HALLMARKS OF CANCER REVIEW EXAM Q & ACANCER BIOLOGY LECTURE 3 CELLULAR HALLMARKS OF CANCER REVIEW EXAM Q & AM Q & A
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Summary Signal Transduction & Hallmarks of Cancer
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A summary of the lectures of signal transduction and hallmarks of cancer with additional questions and a recap after each lecture. 
Part of Bio-Pharmaceutical Sciences Master program - year 2022/2023 
 
Lecture 1 - “Deregulating cellular energetics” 
Lecture 2- Hallmarks of Cancer 
Lecture 3 - Tumor Angiogenesis 
Lecture 4 - Activating invasion and metastasis 
Lecture 5 - How to develop a successful anticancer drug 
Lecture 6 - “Avoiding immune destruction and tumor promoting inflammati...
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CANCER BIOLOGY LECTURE 3 CELLULAR HALLMARKS OF CANCER REVIEW EXAM Q & A
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CANCER BIOLOGY LECTURE 3 CELLULAR HALLMARKS OF CANCER REVIEW EXAM Q & ACANCER BIOLOGY LECTCANCER BIOLOGY LECTURE 3 CELLULAR HALLMARKS OF CANCER REVIEW EXAM Q & AURE 3 CELLULAR HALLMARKS OF CANCER REVIEW EXAM Q & A
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CANCER BIOLOGY LECTURE 3 CELLULAR HALLMARKS OF CANCER REVIEW EXAM Q & A
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CANCER BIOLOGY LECTURE 3 CELLULAR HALLMARKS OF CANCER REVIEW EXAM Q & ACANCER BIOLOGY LECTURE 3 CELLULAR HALLMARKS OF CANCER REVIEW EXAM Q & ACANCER BIOLOGY LECTURE 3 CELLULAR HALLMARKS OF CANCER REVIEW EXAM Q & ACANCER BIOLOGY LECTURE 3 CELLULAR HALLMARKS OF CANCER REVIEW EXAM Q & ACANCER BIOLOGY LECTURE 3 CELLULAR HALLMARKS OF CANCER REVIEW EXAM Q & ACANCER BIOLOGY LECTURE 3 CELLULAR HALLMARKS OF CANCER REVIEW EXAM Q & ACANCER BIOLOGY LECTURE 3 CELLULAR HALLMARKS OF CANCER REVIEW EXAM Q & A
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CANCER BIOLOGY LECTURE 3 CELLULAR HALLMARKS OF CANCER REVIEW EXAM Q & A
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CANCER BIOLOGY LECTURE 3 CELLULAR HALLMARKS OF CANCER REVIEW EXAM Q & ACANCER BIOLOGY LECTURE 3 CELLULAR HALLMARKS OF CANCER REVIEW EXAM Q & A
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GMS 6552 Exam 2 Questions and Answers 100% Correct
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GMS 6552 Exam 2 Questions and Answers 100% CorrectGMS 6552 Exam 2 Questions and Answers 100% CorrectGMS 6552 Exam 2 Questions and Answers 100% CorrectGMS 6552 Exam 2 Questions and Answers 100% Correct 
 
Oncogene - ANSWER-A gene that causes or contributes to the development of cancer 
 
Hallmarks of Cancer - ANSWER-Sustaining proliferative signaling 
Evading growth suppressors 
Activating invasion and metastasis 
Enabling replicative immortality 
Inducing angiogenesis 
Resisting cell death 
 
In...
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(Answered corrcetly) NR509 Final Exam Solution Guide 2022.
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NR509 Final Exam Solution Guide 2022. 
 
A 35-year-old female with a history of migraines presents to the clinic with worsening symptoms for the past few weeks. She reports waking up at night with headaches and nausea. Her only medication history is oral contraceptive pills (OCPs). Otherwise, she states she is healthy. Which of the following actions if taken by the NP is the best next step? 
 
A grandmother is accompanying her 9-year-old granddaughter during a routine physical examination. She ...
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