Glanzmann thrombasthenia - Study guides, Revision notes & Summaries

The McLeod phenotype is associated with which of the following antigen systems? - Rh - P - Kell - MNS - CORRECT ANSWER Kell A deficiency of platelet receptor IIb/IIIa can be found on which of the following? - Glanzmann Thrombasthenia - Von Willebrand disease - Asprin therapy - Bernard-Soulier syndrome - CORRECT ANSWER Glanzmann Thrombasthenia If a disease or disorder causes serum binding proteins (such as albumin) to decrease, what may occur if the dose of a h...

ASCP MLS FINAL Questions 2024 With Verified Answers The majority of the iron in an adult is found as a constituent of: A. hemoglobin B. hemosiderin C. myoglobin D. transferrin (Answer: - A. hemoglobin Which of the following is associated with May-Hegglin anomaly? A. membrane defect of lysosomes B. Dohle bodies and giant platelts C. chronic myelogenous leukemia D. mucopolysaccharidosis (Answer: - B. Dohle bodies and giant platelts Elevation of the granulocyte pe...

A deficiency in GPIIb that results in an inability to bind fibrinogen - Glanzmann Thrombasthenia Activated by thrombin to form a fibrin clot - Fibronigen Activated partial thromboplastin time - 25-35 seconds Anti-coagulant that will inhibit thrombin - Heparin Bleeding disorder which is a deficiency of factor 8 (VIII) X-chromosome linked recessive - Hemophilia A BT should not be used in cases of platelet count less than _____ - 100,000/ microliter Clinical features of hemophilia A - Massiv...

UTHSC Fall 2022 D2 Par 2 Pathology Normally, hydrostatic and osmotic forces are balanced T/F, T/F Normally, a lot net movement of fluid out of vessels, all are removed by lymphatic vessels False, normally a little movement out True Disruption in the balance between Hydrostatic Pressure (HP) and colloid osmotic Pressure(COP) causes movement of fluid out of or into the vessel Hydrostatic Pressure (HP) force exerted by fluid pressing against wall, blood fluid being pushed out of the vessel...

UTHSC Fall 2022 D2 Par 2 Pathology Normally, hydrostatic and osmotic forces are balanced T/F, T/F Normally, a lot net movement of fluid out of vessels, all are removed by lymphatic vessels False, normally a little movement out True Disruption in the balance between Hydrostatic Pressure (HP) and colloid osmotic Pressure(COP) causes movement of fluid out of or into the vessel Hydrostatic Pressure (HP) force exerted by fluid pressing against wall, blood fluid being pushed out of the vessel...

Prostacyclin Correct Answer: produced by the walls of endothelial cells and prevents formation of the platelet plug involved in primary hemostasis by preventing platelet activation and aggregation as well as inducing vasodialation. Epinephrine Correct Answer: agonist used in platelet aggregation studies ristocetin Correct Answer: causes platelets to bind to vWF via their GPIb receptor. A test is abnormal in a vWF deficiency since the platelets cannot bind, which causes lack of adhesion/...

Prostacyclin Correct Answer: produced by the walls of endothelial cells and prevents formation of the platelet plug involved in primary hemostasis by preventing platelet activation and aggregation as well as inducing vasodialation. Epinephrine Correct Answer: agonist used in platelet aggregation studies ristocetin Correct Answer: causes platelets to bind to vWF via their GPIb receptor. A test is abnormal in a vWF deficiency since the platelets cannot bind, which causes lack of adhesion/...

UTHSC Fall 2022 D2 Par 2 Pathology Normally, hydrostatic and osmotic forces are balanced T/F, T/F Normally, a lot net movement of fluid out of vessels, all are removed by lymphatic vessels False, normally a little movement out True Disruption in the balance between Hydrostatic Pressure (HP) and colloid osmotic Pressure(COP) causes movement of fluid out of or into the vessel Hydrostatic Pressure (HP) force exerted by fluid pressing against wall, blood fluid being pushed out of the vessel...

BOC Practice Exam Questions With Verified Answers Which of the following is a dimorphic fungus? - answerblastomyces dermatidis N 3% L 62% Monos 23% Eos 12% - answerFungal Meningitis -elevated EOS indicate fungal infection Branching AFP from BAL in 63 yo woman on chemo; does NOT hydrolyze casein, tyrosine or xanthine - answerNocardia Electrode Ag/AgCl anode and Platinum wire cathode in KCl - what does this probe measure? - answerpO2 AABB minimum Hgb level for AUTOLOGOUS donation - answer...

preview:● Glanzmann’s thrombasthenia – autosomal recessive so you have to inherit a faulty gene from mum and dad, and it is quite rare roughly around 1 in a million. ● Because it is an inherited condition patients will present with symptoms following birth therefore earlier in their life and these include nosebleeds, extensive bruising, bleeding gums, excessive bleeding during periods. ● It arises as we get defects in the glycoprotein 2b3a complex. ● Platelets express a number of ...