Lncrna - Study guides, Revision notes & Summaries

activators - TFs that increase the levels of transcription initiation Adaptive mutations - evolutionary change and adaptation to new environments, stressful conditions darwins birbs AP - activator proteins ARE - AP2 response elements Base analogs (chem induced - 5-bromouracil resembles thymine, except that it has bromine atom in place of methyl on 5' C base excision repair (BER) - repairs damaged base by using AP endonuclease to cleave damage on 5' side and DNA polymerase add new base...

BIO 2120 Exam 2 - Questions and Answers RNA secondary and tertiary structure Defined by base pairing that forms stem-loops, critical for fitting onto the ribosome Genetic code collection of codons of mRNA, each of which directs the incorporation of a particular amino acid into a protein during protein synthesis In vitro translation Protein synthesis in a cell-free extract. How many possible codons are there? 64 61 specify an amino acid 3 are stop codons that signal the termination of protein sy...

Why does RNA contain uracil and DNA contain thymine? Choose the one BEST answer. correct answers Spontaneous cytosine deamination generates uracil, which base pairs with adenine during replication, and thereby converts a C-G base pair to a T-A base pair. RNA is typically more susceptible to backbone hydrolysis than DNA because of a chemical property. correct answers The presence of a 2' OH group Choose 3 reasons why RNA is a dynamic biomolecule, and in that way, distinct from DNA. corr...

GENE 4200 practice exam 1|26 Questions with Verified Answers Transcription factors help regulate which cell types and tissues will express a given gene (T/F) - CORRECT ANSWER When comparing RNA levels for gene X between two samples by qPCR, the sample with thehighest DCT value would have the least gene X RNA (T/F) - CORRECT ANSWER Exons are the most abundant DNA sequences in the human genome (T/F) - CORRECT ANSWER false Most transposons in the human genome are inactive. (T/F) - COR...

genome  complete DNA sequence of a cell or organism  - 2 in humans: nuclear, mitochondrial mitochondrial genome  - Very small (16.6kb long)  - No histones  - Highly redundant  - Compact (no 'extra' DNA)  - DS ring  - Each mito has multiple copies of the mtDNA genome  - 2 rRNA, 22tRNA, 13 oxidative phosphorylation proteins  - High mutation rate (10x nuclear)  - inherited from mother major difference between nuclear and mitochondrial genome cont...

GENE 4200 practice exam 1|26 Questions with Verified Answers Transcription factors help regulate which cell types and tissues will express a given gene (T/F) - CORRECT ANSWER When comparing RNA levels for gene X between two samples by qPCR, the sample with thehighest DCT value would have the least gene X RNA (T/F) - CORRECT ANSWER Exons are the most abundant DNA sequences in the human genome (T/F) - CORRECT ANSWER false Most transposons in the human genome are inactive. (T/F) - COR...

Nucleic Acid - correct answer A polymer (long repeating chain) of nucleotides - covalently bonded together. Deoxyribonucleic Acid (DNA) - correct answer Usually a double helix made up of 2 chains of deoxyribonucleotides. Ribonucleic Acid (RNA) - correct answer Usually a singe-stranded chain of ribonucleotides. Nucleotides - correct answer These are the building blocks of nucleic acids. The contain a central sugar ring (containing an oxygen and several carbons), 1 to ...

Lecture notes on Non-coding RNAs, miRNA and lncRNA

genome - complete DNA sequence of a cell or organism - 2 in humans: nuclear, mitochondrial mitochondrial genome - - Very small (16.6kb long) - No histones - Highly redundant - Compact (no 'extra' DNA) - DS ring - Each mito has multiple copies of the mtDNA genome - 2 rRNA, 22tRNA, 13 oxidative phosphorylation proteins - High mutation rate (10x nuclear) - inherited from mother major difference between nuclear and mitochondrial genome content - nuclear genome has much more extra s...

These lecture notes cover Topic 12, focusing on RNA-based regulation and its effects on gene expression. The notes provide a comprehensive overview of various RNA regulatory mechanisms in both prokaryotes and eukaryotes, including transcription, translation, and chromatin structure changes. Key topics include mRNA secondary structures, riboswitches, antisense RNA, RNA interference (RNAi), and long non-coding RNAs (lncRNAs). Additionally, the notes explore specific examples and experimental appli...