NR 546 Exam Questions with 100% Correct Answers

Prefrontal Cortex Symptoms of MDD Correct Answer Concentration Mental Fatigue Mood PFC & Amygdala Symptoms of MDD Correct Answer Guilt Suicidality Worthlessness Striatum Symptoms of MDD Correct Answer Physical fatigue Nucleus Accumbens Symptoms of MDD Correct Answer Pleasure interests Hypothalamus Symptoms of MDD Correct Answer Sleep Appetite Thalamus & Hypothalamus Symptoms of Mania Correct Answer Decreased sleep/arousal Striatum Symptoms of Mania Correct Answer Motor/agitation Prefrontal cortex (PFC) Symptoms of Mania Correct Answer Risk-taking Talkative/pressured speech Nucleus Accumbens & PFC Symptoms of Mania Correct Answer Racing thoughts, grandiosity PFC & Amygdala Symptoms of Mania Correct Answer Mood Medication Management Correct Answer SSRI-Selective Serotonin Reuptake Inhibitors *Inhibit 5 HT reuptake SNRI-Serotonin Norepinephrine Reuptake Inhibitors *inhibit 5-HT reuptake *inhibit NE reuptake (increase energy, focus) *increase DA in prefrontal cortex (increase cognition) NDRI-Norepinephrine Dopamine Reuptake inhibitors *inhibit DA reuptake (increase alertness, motivation) *inhibit NE reuptake (increase energy) SARI-Serotonin Antagonist Reuptake Inhibitors Selective Serotonin Reuptake Inhibitors (SSRIs): Most adverse effects will subside after 4-5 days once the body adjusts to increased serotonin levels. Correct Answer diarrhea headache weight gain sexual side effects Serotonin Norepinephrine Reuptake Inhibitors (SNRIs): Medications should not be abruptly stopped to avoid discontinuation symptoms. NE effects of the medication may increase anxiety in some clients. Report worsening anxiety to the provider. Correct Answer elevated blood pressure anxiety insomnia constipation Norepinephrine Dopamine Reuptake Inhibitors (NDRI): Take medication in the morning. Stop taking medication if seizures occur. Stop taking medication if anxiety is noted. Correct Answer agitation headache dry mouth constipation weight loss escitalopram (Lexapro) SSRI Correct Answer no known drug interactions best tolerated SSRI 27-32 hour half-life good for forgetful prone clients least CYP reactions Substrate for 3A4 citalopram (Celexa) SSRI Correct Answer mild antihistamine effects; Half-Life: 23-45 hours Weak Inhibitor of 2D6 fluoxetine (Prozac) SSRI Correct Answer longest half-life Use caution in patients with comorbid anxiety due to risk for activation and panic attacks Half-Life: 2-3 days parent, 2 week metabolite Inhibits 2D6 and 3A4 paroxetine (Paxil) SSRI Correct Answer also treats social anxiety and insomnia associated with weight gain will experience withdrawal with missed dose or abrupt stop Half-Life: 24 hours Inhibits 2D6 fluvoxamine (Luvox) SSRI Correct Answer treats anxious depression smokers require an increased dose Half-Life: 9-28 hours Inhibits 3A4, 2C9, 1A2