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IMM250 EXAM QUESTIONS AND CORRECT ANSWERS (ALREADY GRADED A+)
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IMM250 EXAM QUESTIONS AND CORRECT ANSWERS (ALREADY GRADED A+) Which of the following changes is seen at infected sites as a consequence of an acute inflammatory response: - Answer- 1. Recruitment of neutrophils 2. Increased expression of cell adhesion molecules on endothelial cells 3. Edema 4. ...

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  • October 21, 2024
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  • 2024/2025
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IMM250 EXAM QUESTIONS AND
CORRECT ANSWERS (ALREADY
GRADED A+)
Which of the following changes is seen at infected sites as a consequence of an acute
inflammatory response: - Answer- 1. Recruitment of neutrophils
2. Increased expression of cell adhesion molecules on endothelial cells
3. Edema
4. Increased vascular permeability

CRP (C-reactive protein) - Answer- 1. An indicator of infection
2. A PRR
3. An opsonin
4. A protein that can activate complement
5. produced in response to IL-6

Type I IFNs - Answer- 1. They induce the synthesis of enzymes that degrade viral RNA
2. Their production is regulated by transcription factors called IRFs
3. The Type I IFN receptor is ubiquitously expressed

What is true about primary and secondary lymphoid tissues? - Answer- Primary
lymphoid tissues are sites where lymphocytes mature from precursor cells
Secondary lymphoid tissues are sites where mature lymphocytes are activated by
specific antigen

matching of lymphocyte antigen receptor with their properties - Answer- TCR-no
secreted form
BCR-has two antigen binding sites
BCR/TCR-both have variable and constant regions & don't recognize PAMPs

Which best describes the antigen receptors on the cell surface of a lymphocyte? -
Answer- There are many copies of one receptor protein that can bind a single antigen

"A mechanism known as [blank 1] is responsible for the [blank 2] of lymphocyte antigen
receptors, and affects the protein structure of the [blank 3] region of these molecules. " -
Answer- "A mechanism known as gene rearrangement is responsible for the diversity of
lymphocyte antigen receptors, and affects the protein structure of the variable region of
these molecules. "

, Clonal selection involves the idea that: - Answer- Only a lymphocyte clone with a
complementary antigen receptor will be activated by a particular antigen

When a mature lymphocyte is called 'naïve' it is because: - Answer- It has not yet
encountered antigen

Which represents the correct order of steps in lymphocyte activation? - Answer- Antigen
receptor signaling, Costimulatory signaling, Cytokine signaling

Immature dendritic cells are: - Answer- Not very mobile

Mature dendritic cells - Answer- Express B7 costimulatory molecule

During B cell activation, 'linked recognition' refers to the idea that the B and T cell: -
Answer- Recognize different epitopes on the same antigen

Out of 100,000 naive T cells In a given individual, approximately how many would you
expect to be specific for a particular antigen? - Answer- 10

The spleen is a site where: - Answer- Immune responses are activated in response to
blood-borne antigens

Lymphocyte recirculation ensures that naive lymphocytes continually pass through: -
Answer- Secondary lymphoid tissues

Consider the following events ('a' through 'd') that occur at some point during an
adaptive immune response:
a) Clonal expansion and differentiation of antigen-specific T cells
b) Th and CTL are reactivated by specific antigen and perform clearance functions
c) Effector lymphocytes travel to inflamed tissue
d) Costimulation between mature DC and naive T cells
Which sequence below represents the order in which these events occur? - Answer-
1)Costimulation between mature DC and naive T cells
2)Clonal expansion and differentiation of antigen-specific T cells
3)Effector lymphocytes travel to inflamed tissue
4)Th and CTL are reactivated by specific antigen and perform clearance functions

Ilya Mechnikov - Answer- cellular immunology

Paul Ehrlich - Answer- humoral immunology

Louis Pasteur - Answer- 1. fermentation as a process caused by microorganisms
2. the disproval of spontaneous generation of microorganisms
3. the first rabies vaccine(the first cholera vaccine)--> innoculated a person with the
rabies vaccine

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