Imm250 - Study guides, Class notes & Summaries

IMM250 MIDTERM EXAM QUESTIONS AND REVISED ANSWERS NEW UPDATE Which of the following is not a property of adaptive immunity A. Tolerance to self-antigens B. Memory C. High specificity D. Improved secondary responses E. Fast response (within 24 hours) - Answer E. Fast response (within 24 hours) The first antibody isotype expressed by a newly produced B cell in the bone marrow is A. IgA B. lgD C. lgE D. lgG E. lgM - Answer E. lgM IgE are mostly fo...

IMM250 EXAM WITH COMPLETE SOLUTIONS (ALREADY GRADED A+) What happens when pathogen breaches barrier - 5 - Answer- 1 - Release of pamps 2 - Detected by PRR 3 - Activates signal transduction 4 - Activates NFkB 5 - Controls production of soluble mediators Acute inflammatory response - 4 - Answer- 1 - Rest 2 - Bacteria comes in -> cytokines 3 - Vasodilation to increase vascular permeability 4 - Infected tissue becomes inflamed - redness, heat, swelling, pain Pro-inflammatory cytok...

IMM250 PRACTICE EXAM QUESTIONS WITH ALL CORRECT ANSWERS Mechanisms through which neutrophils can kill microbes - Answer- - Antimicrobial peptides - Lysozyme - ROS (reactive oxygen species) - respiratory burst Reactive oxygen species - Answer- ROS are powerful oxidizing factors that kill pathogens - One way that phagocytes kill bacteria is by formation of NADPH oxidase from the combination of subunits(p67, p47, p40 and p22, gp91) which, with O2 forms ROS. Chronic Granulomatous Dise...

IMM250 Midterm UPDATED Questions and CORRECT Answers immune system - CORRECT ANSWER- system of tissues, cells, and soluble products that recognize, attack and destroy foreign entities that might be dangerous pathogens - CORRECT ANSWER- - capable of causing disease in humans - contain virulent factors virulent factors - CORRECT ANSWER- particular proteins in pathogens that help them cause diseas

IMM250 Midterm UPDATED ACTUAL Questions and CORRECT Answers Identify the correct description of the variolation "royal experiment". A. Members of royal family in London were inoculated by Edward Jenner with material obtained from cowpox scabs because cowpox was known to be a microorganism similar to smallpox but less virulent B. Members of royal family in London were inoculated by Edward Jenner first with material obtained from cowpox scabs and, after two weeks, with material obta...

IMM250 Final UPDATED ACTUAL Questions and CORRECT Answers How do barriers defend against infection? - CORRECT ANSWER- Physically and mechanically keep pathogens out. Example: stomach and skin. They do not need to go through a process to get activated; they are immediately active. Summarize innate immunity? - CORRECT ANSWER- It involves cells and molecules that get recruited to the site of infection. Innate cells recognize PAMPs using PRRs. PAMPs are common to a certain group of patho...

IMM250 EXAM NEWEST 2024 ACTUAL EXAM TEST BANK COMPLETE QUESTIONS AND DETAILED ANSWERS (VERIFIED ANSWERS) ALREADY GRADED A+ What is immunodeficiency? - Answer- A disease where there is absent or deficient immune responses. It can affect innate immunity or adaptive immunity and increase the risk of cancer. What is primary immunodeficiency? - Answer- An immunodeficiency that is inherited by genetics What is secondary immunodeficiency? - Answer- An immunodeficiency that is due to external/e...

IMM250 STUDY EXAM QUESTIONS WITH ALL CORRECT ANSWERS What are cytoplasmic PRRs? - Answer- They recognize MAMPs that are inside the cell, includes Nod-like receptors (NLR) and Rig-I-like receptors (RLR) Why do mucosal epithelial cells have low TLR expression? - Answer- For tolerance of epithelium to normal microbiota? What PRRs are prsent in epithelial cells? - Answer- Only the cytoplasmic NLRs and RLRs are present. What do NLRP receptors recognize? - Answer- DAMPs such as K+ and ROS. ...

IMM250 EXAM QUESTIONS AND CORRECT ANSWERS (ALREADY GRADED A+) Which of the following changes is seen at infected sites as a consequence of an acute inflammatory response: - Answer- 1. Recruitment of neutrophils 2. Increased expression of cell adhesion molecules on endothelial cells 3. Edema 4. Increased vascular permeability CRP (C-reactive protein) - Answer- 1. An indicator of infection 2. A PRR 3. An opsonin 4. A protein that can activate complement 5. produced in response to IL-6 ...

IMM250 Final UPDATED Questions and CORRECT Answers innate immunity - CORRECT ANSWER- first line of defense, recognize common molecular patterns, innate leukocyte responses, non "memory" of threat adaptive immunity - CORRECT ANSWER- second line of defense, recognize any molecular structure, lymphocyte responses, "memory" of threat