Glucokinase - Study guides, Class notes & Summaries

NBME Biochemistry Shelf Exam 2024 Updated Questions and Answers What neurotransmitter stimulates release of epinephrine from adrenal medulla? acetylcholine What is a metabolite if epinephrine that suggests epi-secreting carcinoma? What is another assoc symptom? metanephrine; assoc with HBP What does acetazolamide (carbonic anhydrase ib) treat? glaucoma, epilepsy, altitude sickness, congestive heart failure can cause dehydration Sickle cell anemia is due to... pt mutation of Glu -&gt...

NBME PHYSIOLOGY UPDATED EXAM WITH COMPLETE SOLUTIONS 2023/2024 Prostglandin - CORRECT ANSWER-From mast cells, macrophages, EC, and platelets Vasodilation, pain Rate controlling step in Insulin secretion - CORRECT ANSWER-Phosphorylation of glucose by glucokinase Glucokinase mutation - CORRECT ANSWER-Autosomal dominant form of early onset type 2 diabetes GLUT 2 - CORRECT ANSWER-low affinity high capacity glucose transporter. Uptake by beta cells Insulin release - CORRECT ANSWER-Bloo...

NBME PHYSIOLOGY UPDATED EXAM WITH COMPLETE SOLUTIONS 2023/2024 Prostglandin - CORRECT ANSWER-From mast cells, macrophages, EC, and platelets Vasodilation, pain Rate controlling step in Insulin secretion - CORRECT ANSWER-Phosphorylation of glucose by glucokinase Glucokinase mutation - CORRECT ANSWER-Autosomal dominant form of early onset type 2 diabetes GLUT 2 - CORRECT ANSWER-low affinity high capacity glucose transporter. Uptake by beta cells Insulin release - CORRECT ANSWER-Bloo...

MCAT METABOLISMWhile Hexokinase is present in most tissues, GLUCOKINASE is specifically present in ____________ in the liver and pancreatic _____________ cells (acts as a glucose sensor with GLUT2) hepatocytes; B-islet cells Metabolic state 3-5 hours after eating; marked by secretion of ____________ Postprandial; insulin Which state is also known as the ABSORPTIVE or most well-fed state and is marked by anabolism and Insulin release postprandial What 3 organs does insulin tar...

MCAT METABOLISMWhile Hexokinase is present in most tissues, GLUCOKINASE is specifically present in ____________ in the liver and pancreatic _____________ cells (acts as a glucose sensor with GLUT2) hepatocytes; B-islet cells Metabolic state 3-5 hours after eating; marked by secretion of ____________ Postprandial; insulin Which state is also known as the ABSORPTIVE or most well-fed state and is marked by anabolism and Insulin release postprandial What 3 organs does insulin tar...

Which pair of enzymes listed below is unique to gluconeogensis? A. Pyruvate kinase and pyruvate carboxylase B. Phosphoenolpyruvate carboxykinase and pyruvate carboxylase C. Fructose bisphosphatase and phosphofructokinase D. Pyruvate dehydrogenase and glucose 6-phosphataseAnswer - B. Phosphoenolpyruvate carboxykinase and pyruvate carboxylase Which 2 polysaccharides contain the same types of bonds? A. Cellulose and amylose B. Amylopectin and glycogen C. Glycogen and cellulose D. Amylo...

Which pair of enzymes listed below is unique to gluconeogensis? A. Pyruvate kinase and pyruvate carboxylase B. Phosphoenolpyruvate carboxykinase and pyruvate carboxylase C. Fructose bisphosphatase and phosphofructokinase D. Pyruvate dehydrogenase and glucose 6-phosphataseAnswer - B. Phosphoenolpyruvate carboxykinase and pyruvate carboxylase Which 2 polysaccharides contain the same types of bonds? A. Cellulose and amylose B. Amylopectin and glycogen C. Glycogen and cellulose D. Amylo...

Hexokinase can phosphorylate fructose, glucose, or mannose with high affinity and low capacity traps in the cell uses one ATP muscle tissue Glucokinase can phosphorylate glucose with low affinity and high capacity traps in the cell uses one ATP liver, brain, pancreas, and gut tissues Phosphoglucoisomerase catalyzes isomerization of glucose-6-phosphate to fructose-6- phosphate reversible; direction dictated by concentrations enediol intermediate

a-D-glucose + ATP ---> ________ + ________ + H+ correct answer: a-D-glucose-6-phosphate + ADP For the first five steps of glycolysis, the appropriate sequence of enzymes is: a. phosphofructokinase-1 (PFK-1) b. hexokinase/glucokinase c. fructose bisphosphate aldolase d. phosphoglucoisomerase e. triose phosphate isomerase (TPI) correct answer: B, D, A, C, E Hexokinase and glucokinase belong to the kinase subclass of what class of enzymes? correct answer: transferase In the ...

46. Which method of directly regulates PFK-I? A) feedback inhibition by fructose 2,6-bisphosphate B) feed forward activation by phosphoenolpyruvate C) allosteric activation by AMP D) its phosphorylation in response to glucagon signaling E) allosteric activation by citrate 47. Which statement regarding regulation of glycolysis and gluconeogenesis is FALSE? A) Phosphofructokinase-1 and fructose 1,6-bisphosphatase are PRevented from forming a futile cycle by reversible covalent modificatio...