Logp - Samenvattingen, Notities en Examens

ILE 3 - Final Exam Questions And Answers 100% Correct (2024 New Update) I - ANS-biopharm class ___ has a high solubility and high permeability II - ANS-biopharm class ___ has a low solubility and a high permeability III - ANS-biopharm class ___ has a high solubility and a low permeability IV - ANS-biopharm class ___ has a low solubility and a low permeability metoprolol - ANS-example from class of drug in biopharm class I carbamazepine - ANS-example from class of drug in biopharm class II ...

GMS 6504 Exam Questions and Answers 100% CorrectGMS 6504 Exam Questions and Answers 100% CorrectGMS 6504 Exam Questions and Answers 100% CorrectGMS 6504 Exam Questions and Answers 100% CorrectLipinski's rule of 5 - ANSWER-- Poor absorption or permeation are more likely when: 1. mass greater than 500 Da 2. highly lipophilic - logP > 5 3. more than 5 hydrogen bond donors 4. more than 10 hydrogen bond acceptors Partition coefficient - ANSWER-p = C(octanol)/C(water) - ratio of the equili...

GMS6504 #2 Questions And Answers With Verified Solutions what are the four things that make a good drug versus a bad one? 1. Lipinski's Rule of 5 2. Chemical reactivity: good or bad? 3. Some chemically or biologically reactive functional groups to recognize 4. Choosing a target explain the old lipinskis rule of 5 and the rules Poor absorption or permeation are more likely when: 1. Molecular mass greater than 500 Da (want small and absorbable) 2. High lipophilicity (expressed as LogP...

GMS6504 Exam 2 Questions And Answers With Real Tests What are the 4 things that make something a good drug? ANS 1. Lipinski's Rule of 5 2. Chemical reactivity: good or bad? 3. Some chemically or biologically reactive functional groups to recognize 4. Choosing a target What is Lipinski's Rule of 5? ANS 1.Molecular mass greater than 500 Da 2.High lipophilicity (expressed as LogP greater than 5) 3.More than 5 hydrogen bond donors 4.More than 10 hydrogen bond acceptors Par...

Dit document bevat oefententamenvragen om je voor te bereiden op het tentamen voor BA-102: Chemie van geneesmiddelen voor de studie Farmacie aan de universiteit Utrecht. Deze toets bevat vragen over o.a. chirale atomen, functionele groepen, hydrolyse, lambert beer, pKa en pH, eiwitstructuren, resonantiestructuren, aromaticiteit, tekenen van structuren, logP. Er is geprobeerd een zo goed mogelijke indruk te geven van het echte tentamen. Het kan zijn dat niet alles in dit oefententamen getoets...

GMS 6504 Exam Questions and Answers 100% CorrectGMS 6504 Exam Questions and Answers 100% CorrectGMS 6504 Exam Questions and Answers 100% CorrectGMS 6504 Exam Questions and Answers 100% CorrectLipinski's rule of 5 - ANSWER-- Poor absorption or permeation are more likely when: 1. mass greater than 500 Da 2. highly lipophilic - logP > 5 3. more than 5 hydrogen bond donors 4. more than 10 hydrogen bond acceptors Partition coefficient - ANSWER-p = C(octanol)/C(water) - ratio of the equili...

I - Answer- biopharm class ___ has a high solubility and high permeability II - Answer- biopharm class ___ has a low solubility and a high permeability III - Answer- biopharm class ___ has a high solubility and a low permeability IV - Answer- biopharm class ___ has a low solubility and a low permeability metoprolol - Answer- example from class of drug in biopharm class I carbamazepine - Answer- example from class of drug in biopharm class II metformin - Answer- example from cla...

Lipinski's rule of 5 - ANSWER-- Poor absorption or permeation are more likely when: 1. mass greater than 500 Da 2. highly lipophilic - logP > 5 3. more than 5 hydrogen bond donors 4. more than 10 hydrogen bond acceptors Partition coefficient - ANSWER-p = C(octanol)/C(water) - ratio of the equilibrium concentrations of dissolved substance in a two-phase system containing two largely immiscible solvents (water & octanol) - Log10(P) Improved Lipinski Parameters - ANSWER-1. Partition...

GMS 6504 Review Exam 2 Questions And Answers With Complete Updates In terms of Lipinski's rules, which of the following functional groups serves as a hydrogen bond donor? A. -Cl B. -NO2 C. =O D. -SO3 E. -NH2 E. -NH2 Will a hydrophobic molecule have a high or low logP? A. High B. Low A. High Which is the best explanation as to why CNS drugs tend to have smaller polar surface areas than drugs that target things outside of the CNS? A. The receptors in the CNS tend to be small prot...

Antibodies and RNA-based therapeutics belong to a new class of therapeutics called "biologics". - Answer True Dosage form of a medication usually has little to do with clinical effectiveness of the drug. - Answer False The "Pharmacokinetics" of a drug refers to the time course of drug concentration in the body after administration, and most often in the systemic circulation. - Answer True Clinical factors (e.g. diseases, genetics, age), but not dosing regimen (e.g. dose, dosag...