Cyp2d6 Study guides, Class notes & Summaries

Exam 4: NURS660/ NURS 660 (NEW 2023/ 2024) Psychopharmacology and Advanced Mental Health Exam | 100% Correct | Complete guide with Questions and Verified Answers - Maryville Question Inhibitors/Inducers - which are you most concerned with when considering the CYP450 pathways? Answer: Inhibitors Question What are 3 phych meds are we most worried about with Strattera? Why?- Answer: Paxil, Prozac, Wellbutrin; they are inhibitors on CYP2D6 Question ...

Cyproheptadine Answer- 5-HT2A receptor antagonist Serotonin syndrome Answer- Caused by excessive stimulation of 5-HT2A receptors and possibly 5-HT1A receptors In patients withdrawing from both hypnotic - sedatives and CNS stimulants, which is treated first? Answer- hypnotic - sedatives For those patients on both opiates and sedative-hypnotics, which should be tapered first? Answer- Taper the sedative-hypnotic first while keeping the opiate dose set at a stable level. Once off the sediti...

ADME correct answer: Absorption Distribution Metabolism Elimination When a drug is absorbed, it can be one of 2 things correct answer: 1. Free drug (unbound, active and can readily cross cell membranes) 2. Protein-bound (usually inactive) Binding of drugs to receptors correct answer: Non-specific binding <——> specific binding —> desired biological effect **Distribution** Pharmacokinetics correct answer: Metabolism and elimination -what the body does to the dru...

GCU NUR 635 MIDTERM EXAM REVIEW QUESTIONS AND ANSWERS, GRADED A+ Pharmacokinetics includes - -absorption, distribution, metabolism, elimination absorption of drugs factors - -PH changes, gastric emptying, gastric enzymes, bile acids, GI flora, food and nutrient interactions, lipid solubility Where is cyp450 system found - -endoplasmic reticulum of hepatocytes CYP3A4/5 - -most abundant CYP450 isoform which metabolizes the most prescribed " "drugs. Especially important for bioavailabili...

NURS 663 EXAM 1/ Study Guide Maryville question well solved!2022/2023SIADH Syndrome of inappropriate antidiuretic hormone secretion (SIADH) is a condition in which the body makes too much antidiuretic hormone (ADH). This hormone helps the kidneys control the amount of water your body loses through the urine. SIADH causes the body to retain too much water Causes of SIADH ... Carbamazepine (Tegretol) Is primarily metabolized by ______ (cytochrome P450) Is primarily metabolized ...

Sertraline (Zoloft) Major Side Effects Answer insomnia, somnolence, HA, dry mouth, sex dysfunction, nausea & diarrhea Fluoxetine (Prozac) Major Side Effect Answer Activating (UPPER); AGITATION, INSOMNIA, nausea, vomiting, sex dysfunction, GI, serotonin syndrome Paraoxetine (Paxil) Major Side Effects Answer Anticholinergic (can't see, can't sleep, can't shit, can't spit), CYP2D6 inhibitor, increases TCA, phenothiazines, Type 1C antiarrhythmics, weight gain, GI, sex dysfuncti...

Which CYP-interacting drugs increase the levels of propranolol and metoprolol? correct answer: CYP2D6 inhibitors (e.g. amiodarone, paroxetine) How does digoxin benefit CHF? Atrial fibrillation? correct answer: Digoxin is a mild positive ionotrope to help HF and is a negative chronotrope to help Afib. Which beta-blocker is more likely to cause CNS side effects, such as depression and insomnia? Why correct answer: Propranolol will have more CNS side effects due to its greater lipid solubi...

Pharm Exam Questions And Answers (Verified And Updated) A provider considers prescribing tamoxifen for a woman with breast cancer. Upon reviewing results of genetic testing, the prescriber notes that the patient has variations in the CYP2Dyallele resulting in a deficiency of the CYP2D6 isoenzymes. What action will this deficiency warrant in the prescribing of tamoxifen, a CYP2D6 substrate? A. The tamoxifen will not be prescribed. B. The individual doses of tamoxifen will be increased. C....

NR 565 Pharm Midterm Exam Questions With Answers @ 2023...

Addiction Medicine Exam CSAM Cyproheptadine - CORRECT ANSWER-5-HT2A receptor antagonist Serotonin syndrome - CORRECT ANSWER-Caused by excessive stimulation of 5-HT2A receptors and possibly 5-HT1A receptors In patients withdrawing from both hypnotic - sedatives and CNS stimulants, which is treated first? - CORRECT ANSWER-hypnotic - sedatives For those patients on both opiates and sedative-hypnotics, which should be tapered first? - CORRECT ANSWER-Taper the sedative-hypnotic first while ke...