Melphalan - Study guides, Class notes & Summaries

NURS 5461 FINAL QUIZ EXAM QUESTIONS AND ANSWERS WITH COMPLETE SOLUTIONS VERIFIED Renal issues that occur with normal aging Decreased GFR, decreased diluting capacity, decreased concentration ability, decreased sodium conservation (volume depletion) decreased sodium excreation (salt sensitivity/HTN), decreased ammonium & bicarb production (metabolic acidosis) Most accurate indicator of renal function in older adults GFR - declines 8mls per decade starting at age 40 Small amounts of protein...

CPHON Examples of Alkylating Agents - correct answer Carboplatin, Cisplatin, Carmustine, Lomustine, Cytoxan, Ifosfamide, Melphalan, Temozolomide, Thiotepa Examples of Antimetabolites (Cell-cycle Specific) - correct answer MTX, 5-FU, ARA-C, 6-MP, 6-TG Examples of Plant Detrivatives (Cell-cycle Specific) - correct answer Etoposide, irinotecan, vincristine Examples of Antibiotics for Cancer treatment - correct answer Dactinomycin, Bleomycin Examples of Anthracyclines - correct answer D...

BMTCNCyclophosphamide - correct answer anemia, leukopenia, thrombocytopenia N/V, mucositis/stomatitis, diarrhea hepatotoxicity/HSOS Hemorrhagic cystitis, nephrotoxicity electrolyte imbalances cardiotoxicity, fibrosis pneumonitis infertility alopecia erythema headaches/AMS 2ndary malignancy nasal congestion conjunctivitis Carboplatin - correct answer A/L/T N/V, mucos/stomatitis diarrhea, constipation nephrotoxicity, electrolyte imbalances dermatitis, alopecia hypersensitivity...

Heart: 5 Possible Drugs Correct Answer: Doxorubicin Daunorubicin Idarubicin Mitoxantrone Cyclophosphamide Mood: 1 Possible Drug Class Correct Answer: Corticosteroids Neurotoxicity: 3 Possible Drugs Correct Answer: Vincristine Nelarabine Ifosfamide Ototoxicity: 2 Possible Drugs 2 Correct Answer: Carboplatin Cisplatin Pulmonary Edema/Capillary Leak: 2 Possible Drugs Correct Answer: Clofarabine Cytarabine Diarrhea: Main Drug Correct Answer: Irinotecan Pulmonary Fibrosis: 1 Poss...

What type of transplants commonly have PTLD as a secondary malignancy? - ANSWER-Allo HSCT with T-cell depleted graft Therapies associated with therapy-related acute leukemia and MDS - ANSWER-alkylating agents (eg. Cytoxan, cisplatin, melphalan, busulfan, ifos) , radiation, topoisomerase II inhibitors (eg. doxorubicin, etoposide, mitoxantrone) Genetic predispositions that increase risk of primary and secondary cancers - ANSWER-neurofibromatosis type 1, Fanconi anemia Risk factors for PTLD ...

BMTCN Review Chapter 4 - Transplant Preparative Regimens, Cellular Infusion, Acute Complications, and EngraftmentTRANSPLANT PREP REGIMENS - correct answer Treatment leading up to transplant Acronyms: Ara-C BCNU BU Cy DLT SCT TBI - correct answer Cytarabine Carmustine Busulfan Cyclophosphamide Dose limiting toxicity DStem cell transplant Total body irradiation Induction chemotherapy - correct answer The first treatment given for a disease. It is often part of a standard set of ...

when chemo is used before primary treatment (surgery) to reduce the size of a tumor Correct Answer: neoadjuvant therapy neoadjuvant therapy is common for what 2 kind of cancers? Correct Answer: colon and breast when chemo is used after primary (surgery, radiation) Correct Answer: adjuvant induction Correct Answer: start of chemo consolidation Correct Answer: testing labs and such after chemo myeloblation Correct Answer: destroying the bone marrow in order to a transplant for leukemias...

vesicants - ANSWERbleomycin, carmustine, cisplatin, daunorubicin, doxorubicin, etposide, idarubicin, melphalan, taxol, vincristine cisplatin antidote - ANSWERsodium thiosulfate doxorubicin antidote - ANSWERDexrazoxane vincristine antidote - ANSWERhyaluronidase Alkylating agents - ANSWERbusulfan, cytoxan, melphalan, ifosfamide, carmustine; cell cycle non-specific; affects heme, GI, reproductive antimetabolites - ANSWERmethotrexate, 5-FU, cytarabine, gemcitabine, fludarabine; cell cycle speci...

What type of transplants commonly have PTLD as a secondary malignancy? - ️️Allo HSCT with T-cell depleted graft Therapies associated with therapy-related acute leukemia and MDS - ️️alkylating agents (eg. Cytoxan, cisplatin, melphalan, busulfan, ifos) , radiation, topoisomerase II inhibitors (eg. doxorubicin, etoposide, mitoxantrone) Genetic predispositions that increase risk of primary and secondary cancers - ️️neurofibromatosis type 1, Fanconi anemia Risk factors for PTLD -...

vesicants bleomycin, carmustine, cisplatin, daunorubicin, doxorubicin, etposide, idarubicin, melphalan, taxol, vincristine cisplatin antidote sodium thiosulfate doxorubicin antidote Dexrazoxane vincristine antidote hyaluronidase Alkylating agents busulfan, cytoxan, melphalan, ifosfamide, carmustine; cell cycle non-specific; affects heme, GI, reproductive antimetabolites methotrexate, 5-FU, cytarabine, gemcitabine, fludarabine; cell cycle specific, affect counts & GI platinum co...