Integrins - Study guides, Class notes & Summaries

NBME PATHOLOGY EXAM WITH LATEST VERIFIED QUESTIONS AND 100% CORRECT ANSWERS GRADED A+ Apoptosis: - ANS-Programmed cell death. REQUIRES ATP. Can occur via the intrinsic or extrinsic pathways, both of which involve activation of cytosolic caspases which mediate cellular breakdown. ***Unlike necrosis, apoptosis does not involve significant inflammation. Involves eosinophilic cytoplasm, cell shrinkage, pyknosis and basophilia, membrane blebbing and karyorrhexis, and formation of apoptot...

Tissue resident sentinel cells include (3 types) Dendritic cells, macrophages, and mast cells Circulating leukocytes involved in innate response (2 types) Monocytes and neutrophils Phagocytic immune cells (2 types) Macrophages and neutrophils Difference between macrophages and neutrophils? Neutrophils are short lived and will undergo apoptosis after eating a microbe; macrophages are longer-lived and will eat apoptotic cells and waste General cytokine role in innat...

USABO Open Final Exam 2024 Questions and Answers. Questions 1 and 2. Please use the following options to answer the following three questions. Each choice may be used once, more than once, or not at all. A. Actin. B. Myosin. C. Dynein. D. Kinesin. E. Cyclin. 1. In the extracellular matrix of an animal cell, you would like to test the binding partner of integrins in vitro. Integrins would most likely require firm attachment to which of the above option? A 2. You are working with Dr. Lee...

Name the five types of Cell Adhesion Molecules? Which type enables cells to detect and interact with components of the extracellular matrix? correct answers 1. Cadherins 2. Immunoglobulin Superfamily (IGSF) 3. Selectins 4. Integrins 5. Mucins Integrins allow cells to interact with the surrounding environment or components of the ECM. What are the layers of the epidermis from most superficial to most deep? correct answers Stratum corneum Stratum lucidum Stratum granulosum Stratum spi...

Immunology Exam 1 - BIOL 5500 combatting multicellular parasites or helminths What are the major function of eosinophils? source of cytokine IL-4 which INITIATES allergic response What is the major function of Basophils? Major mediators of CARRYING OUT allergic reactions What is the major function of mast cells? basophils and mast cells Which two granulocytes have the most in common? 24 hours What is the half life of a neutrophil? neutrophils Which granulocyte is ...

USABO Open Final Exam 2024 Questions and Answers. Questions 1 and 2. Please use the following options to answer the following three questions. Each choice may be used once, more than once, or not at all. A. Actin. B. Myosin. C. Dynein. D. Kinesin. E. Cyclin. 1. In the extracellular matrix of an animal cell, you would like to test the binding partner of integrins in vitro. Integrins would most likely require firm attachment to which of the above option? A 2. You are working with Dr. Lee...

USABO Open Final Exam 2024 Questions and Answers. Questions 1 and 2. Please use the following options to answer the following three questions. Each choice may be used once, more than once, or not at all. A. Actin. B. Myosin. C. Dynein. D. Kinesin. E. Cyclin. 1. In the extracellular matrix of an animal cell, you would like to test the binding partner of integrins in vitro. Integrins would most likely require firm attachment to which of the above option? A 2. You are working with Dr. Lee...

MTM Exam 2024 | Questions with 100% Correct Answers What do integrins do? - ANSWER Link all cells together by linking the intracellular matrix to actin Describe the types of protein transport across cell membranes - ANSWER 1. Simple: small uncharged molecules 2. Facilitated diffusion: -Membrane proteins which form hydrophilic channels, fast, show some selectivity but are generally non-directional

Tissues made up of two things - -cells -extracellular matrix (extracellular space) What is the extracellular matrix - -complex network of macromolecules in the extracellular space between cells What is the Extracellular matrix made of? - -polysaccharides and proteins that are made and scripted locally to form meshwork in close association with the cells producing them Where is the Extracellular Matrix plentiful? - -CT What forms the framework of the body? - -CT (bone, skin, tendons, lens ...

IMM250 EXAM WITH COMPLETE SOLUTIONS (ALREADY GRADED A+) What happens when pathogen breaches barrier - 5 - Answer- 1 - Release of pamps 2 - Detected by PRR 3 - Activates signal transduction 4 - Activates NFkB 5 - Controls production of soluble mediators Acute inflammatory response - 4 - Answer- 1 - Rest 2 - Bacteria comes in -> cytokines 3 - Vasodilation to increase vascular permeability 4 - Infected tissue becomes inflamed - redness, heat, swelling, pain Pro-inflammatory cytok...

Extracellular Matrix (ECM) - The ECM provides structural support to the cell and also plays a role in cell signaling. -Components: • Collagen • Glycoproteins (proteins with an oligosaccharide) • GAGs (long polysaccharide chains with amino sugars) • Proteoglycans (a core protein with one or more GAG chains connected) - Composed mostly of water. All of those proteins, glycoproteins, and proteoglycans are dissolved and assembled within a watery medium and most typically the protein ...