PHARM - Bowel Preps for Colonoscopy Questions
with Correct Answers
(Brief) Colorectal Cancer Correct Answer-*3rd most common* cancer
diagnosed in both men and women in the US.
*2nd leading* cancer *killer*
Lifetime risk: about 1 in 21 (4.7%) (which is down from 1 in 20 (a 5%
risk) from 2015).
This risk is slightly *lower in women* than in men.
Preventable? Correct Answer-*YES!*
*Polyp-related* colorectal cancer can be
prevented!
The disease develops from benign polyps (mushroom-
like growths on the lining of the colon and rectum).
*Removing these polyps* before they become cancerous
may prevent cancer from developing.
,Colorectal cancer can be cured in up to *90%* of people when it is
discovered in its *early stages*
COLONOSCOPY Correct Answer-is the *GOLD STANDARD* for
diagnosis.
Bowel Preparations Correct Answer-
Why are there so many options? Correct Answer-because there is no
gold standard
still haven't found the perfect one
Brief History of Bowel Preps Correct Answer-Early preps used dietary
limitations, cathartics and enemas
Were time consuming (48-72hrs), uncomfortable for patient, and
associated with fluid and electrolyte disturbances
1980: *Polyethylene Glycol* (PEG) was formulated, which heralded the
modern age of bowel cleansing --> quickly became the *gold standard*
Intense salty taste, bad smell of sulfates and large volume (4L) led to
poor patient compliance
, Preps continue to evolve --> no perfect one yet! But a good quality one
is essential!
Quality of Bowel Prep: Why Does It Matter? Correct Answer-Thorough
mechanical preparation of the colon is essential for efficient, safe and
complete endoscopic examination!
Bowel preparation is inadequate in up to 25% of patients undergoing
colonoscopy (US Multi-Society Task Force on Colorectal Cancer
(2013))
Consequences of inadequate prep:
- Increased *difficulty of colonoscopy*
- *Prolonged procedure time*
- *Reduced cecal intubation rates*
- *Repeat procedures and shorter surveillance intervals*
- *Reduced adenoma detection rates*
- Exposure to *higher malpractice risk*
with Correct Answers
(Brief) Colorectal Cancer Correct Answer-*3rd most common* cancer
diagnosed in both men and women in the US.
*2nd leading* cancer *killer*
Lifetime risk: about 1 in 21 (4.7%) (which is down from 1 in 20 (a 5%
risk) from 2015).
This risk is slightly *lower in women* than in men.
Preventable? Correct Answer-*YES!*
*Polyp-related* colorectal cancer can be
prevented!
The disease develops from benign polyps (mushroom-
like growths on the lining of the colon and rectum).
*Removing these polyps* before they become cancerous
may prevent cancer from developing.
,Colorectal cancer can be cured in up to *90%* of people when it is
discovered in its *early stages*
COLONOSCOPY Correct Answer-is the *GOLD STANDARD* for
diagnosis.
Bowel Preparations Correct Answer-
Why are there so many options? Correct Answer-because there is no
gold standard
still haven't found the perfect one
Brief History of Bowel Preps Correct Answer-Early preps used dietary
limitations, cathartics and enemas
Were time consuming (48-72hrs), uncomfortable for patient, and
associated with fluid and electrolyte disturbances
1980: *Polyethylene Glycol* (PEG) was formulated, which heralded the
modern age of bowel cleansing --> quickly became the *gold standard*
Intense salty taste, bad smell of sulfates and large volume (4L) led to
poor patient compliance
, Preps continue to evolve --> no perfect one yet! But a good quality one
is essential!
Quality of Bowel Prep: Why Does It Matter? Correct Answer-Thorough
mechanical preparation of the colon is essential for efficient, safe and
complete endoscopic examination!
Bowel preparation is inadequate in up to 25% of patients undergoing
colonoscopy (US Multi-Society Task Force on Colorectal Cancer
(2013))
Consequences of inadequate prep:
- Increased *difficulty of colonoscopy*
- *Prolonged procedure time*
- *Reduced cecal intubation rates*
- *Repeat procedures and shorter surveillance intervals*
- *Reduced adenoma detection rates*
- Exposure to *higher malpractice risk*
