Exam (elaborations)
Midterm exam(only question)
- Course
- Biology 1001A
- Institution
- University Of Western Ontario (UWO )
Midterm exam with only question for first year biology.
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Question 1Imagine your friend discovers a new unicellular organism that has a DNA genome and
ribosomes but no other cytoplasmic organelles.
Which Domain of life would this new organism belong to?
A. Archaea
B. Bacteria
C. Eukarya
D. A or B is possible.
Question 2.
The sporophyte stage of the fern plant, Ophioglossum pycnostichum has an amazing 630
pairs of homologous chromosomes in each cell. (Recall that you have only 23 pairs.)
How many chromosomes would be present in a dividing gametophyte cell at metaphase
of mitosis?
A. 315
B. 630
C. 1260
D. 2520
E. 5040
Question 3
Imagine that students from your study group prepared these
sketches to illustrate the semi-discontinuous replication of DNA in
a replication bubble. Which sketch is accurate assuming that the
5’ end of the top strand is on the right?
Question 4.
Some cancer tumors increase in size because their cells are rapidly dividing “out of control”.
If you cut a cross section through such a tumor and observed the cells with a microscope,
which stage of the cell cycle would most of the cells be in?
A. G0
B. Interphase
C. Mitosis
D. Cytokinesis
,Question 5.
The drug 5-bromouracil (5BU) is used to treat certain forms of cancer. This toxic compound
resembles thymine (T) and is incorporated into growing DNA chains across from adenine
(A).
If 5BU is provided to a cancer cell entering S phase, where will this drug be found in the
chromosomes of newly formed daughter cells following mitosis?
A. All of the chromosomes inherited by all daughter cells would contain 5BU.
B. Only half of the chromosomes inherited by any given daughter cell would contain 5BU.
C. Only half of the daughter cells would have 5BU in all of their chromosomes; the other
half of the daughter cells would have no 5BU in their chromosomes.
Question 6.
This image shows dividing cells with their
chromosomes stained similar to the preparations you
observed in the lab. Although the cytoskeleton is not
visible in this image, which cell would most likely
have had kinetochore motor proteins actively moving
along microtubules?
Question 7.
What role do cell cycle checkpoints play in the “inheritance of sameness”?
1. Checkpoints ensure that DNA polymerase does not read the wrong template strand.
2. Checkpoints ensure that all kinetochores are attached to spindles before anaphase.
3. Checkpoints ensure that organelles are properly replicated.
4. Checkpoints ensure that damage is repaired before DNA is replicated.
A. 1, 2 and 3
B. 1 and 3
C. 2 and 4
D. 4 only
E. All of 1, 2, 3 and 4 are correct.
Question 8.
The table below summarizes a survey of cells in various stages of mitosis in plant
meristem tissue.
Stage of mitosis Number of cells % of total cells
Prophase 22 44
Metaphase 5 10
Anaphase 7 14
Telophase 16 32
Total # cells 50
What can you conclude from these data?
A. Meristem cells divide faster than other plant cells.
B. Telophase follows anaphase.
C. Meristem cells don’t go through interphase.
D. Prophase is the longest phase during mitosis.
, Question 9.
Imagine that you isolate some cells in metaphase of meiosis I from a rat and prepare them
on slides for immunofluorescence light microscopy with staining for chromatin and the
cytoskeleton. Imagine that you do the same for cells in metaphase of mitosis from the
same animal. You have two sets of slides but you forget to label them and they become
mixed up. Which of the following observations would allow you to distinguish the mitosis
slides from the meiosis slides?
A. Only cells on the meiosis slides would have sex chromosomes.
B. Only cells on the meiosis slides would show homologues paired together.
C. Only cells on the mitosis slides would contain microtubules attached to centromeres.
D. Cells on the meiosis slides would have half as many chromosomes as those on the
mitosis slides.
E. Cells on the mitosis slides would have replicated chromosomes (composed of two
chromatids each); cells on the meiosis slides would have unreplicated chromosomes.
Question 10.
When does non-disjunction occur during meiosis?
A. Non-disjunction occurs when homologous pairs fail to undergo recombination.
B. Non-disjunction occurs when homologous pairs fail to separate to opposite poles in
meiosis I.
C. Non-disjunction occurs when homologous pairs fail to separate to opposite poles in
meiosis II.
D. Non-disjunction occurs when homologous pairs fail to enter the same cell at fertilization.
Question 11.
“Interkinesis” is the name of the period between the end of meiosis I and the beginning of
meiosis II. Which of the following is true during interkinesis?
1. Cells are haploid.
2. Sister chromatids are likely identical.
3. Chromosomes have two chromatids.
4. S phase prepares for meiosis II.
A. 1, 2 and 3
B. 1 and 3
C. 2 and 4
D. 4 only
E. All of 1, 2, 3 and 4 are correct.
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