Discovery Lab Exam Bundle Graded A

What is the Chemical Manufacturing and Control group (CMC) - ANSWER-The group that typically deals with how and where the compound will be prepared. Their first task is to optimize the synthesis of the drug, with an eye toward performing the reaction on very large scale...many reactions that we take...

Innate immune system - ANSWER-nonspecific defense mechanisms that come into play immediately or within hours of an antigen's appearance in the body -antigens are foreign substances such as toxins, bacteria, viruses -the defense mechanisms involve physical barriers such as skin, chemicals in blood...

gene knockout - ANSWER-genetic manipulation in which one or more of an organism's genes are prevented from being expressed Genome - ANSWER-the complete instructions for making an organism, consisting of all the genetic material in that organism's chromosomes Genomics - ANSWER-study of whole ...

ESI - ANSWER-electronically stored info EDRM model - ANSWER-tool that is a method for reducing huge amounts of data and culling of what is relevant Decade that mainframes were used - ANSWER-1950s Decade when universities and the government were using the ARPANET - ANSWER-1960s precursor ...

From the very beginning of litigation, what must I do? - ANSWER-have a plan / have the info I need to devise a plan What issues do I have to figure out with e-evidence from the very beginning of litigation? - ANSWER-What e-evidence may be in issue? Where is the data located? Who might have cust...

Lipinski's Rule of 5 - ANSWER-A successful drug meets these criteria: -LogP<5 -molecular weight <500 g/mol - hydrogen bond donors <5 -hydrogen bond acceptors <10 -rotatable bonds<10 logD - ANSWER-distribution between all forms of drug (logD<5) Polar surface area - ANSWE...

Process of Science - ANSWER--exploration and discovery -testing ideas -community analysis and feedback -benefits and outcomes Exploration and discovery - ANSWER--making observations -asking questions -sharing data and ideas -finding inspiration -exploring the literature Testing ideas ...

process of science - ANSWER--exploration and discovery -testing ideas -community analysis and feedback -benefits and outcomes exploration and discovery - ANSWER--making observations -asking questions -sharing data and ideas -finding inspiration -exploring the literature testing i...

What are the parts of the process of science? - ANSWER--exploration and discovery -testing ideas -community analysis and feedback -benefits and outcomes What occurs during exploration and discovery? - ANSWER--making observations -asking questions -sharing data and ideas -finding inspi...

define science - ANSWER-science is a process of discovery that allows us to connect isolated facts into coherent and comprehensive understandings of our world and the universe why is science important? - ANSWER-1) improve the quality of life 2) answer the important questions what type of judg...

newspaper articles often refer to a discovery as "sientific" or claim that somethin has been proved "scientifically". what is meant by this? - ANSWER-that a discovery was made using methods relating to science. there was data collected in a controlled setting to give support to said discovery ...

Which of the following levels of life's hierarchy is not appropriate when referring to two of life's domains, Archaea and Bacteria? - ANSWER-The organ level Darwin proposed the theory of natural selection. For the most part, natural selection acts as a filtering agent at the ___________ level o...

Describe the qualities of an ideal drug target. - ANSWER-an enzyme with a critical function in a biochemical pathway of central importance to the bacterial cell What were the sources of drug discovery in first generation approaches? - ANSWER-Based on antimicrobial activity or systematic screens o...

Scientific method - ANSWER-a method of investigation involving observation and theory to test scientific hypotheses Null hypothesis - ANSWER-A statement or idea that can be falsified, or proved wrong. Scientific theory - ANSWER-a well-tested explanation for a set of observations or experimenta...

Metamorphosis - ANSWER-transformation of an immature organism to an adult Pupa - ANSWER-enclosure in which metamorphosis takes place; a cocoon is an example Larva - ANSWER-an immature form that undergoes metamorphosis Eclose - ANSWER-emerge from a pupal case Instar - ANSWER-a phase of de...

What is the order of the drug discovery and development process - ANSWER-Discover, preclinical, clinical, FDA review What is in vitro - ANSWER-"in glass" research outside body What is in vivo - ANSWER-in life How long does the discovery step take - ANSWER-4-5 years How long does the pr...

Pre-Trial Discovery: PAID MAID - ANSWER-P - PHYSICAL exam A - Request for ADMISSIONS I - Written INTERROGATORIES D - DEPOSITIONS (a.k.a. "examinations before trial") M - MENTAL exam A - Demand for ADDRESSES I - INSPECTION of evidence D - DISCOVERY of evidence ("Discovery & Inspectio...

A physicist at a research laboratory reports a startling new discovery. However, other scientists are unable to reproduce the results of the experiment. Which statement provides the most likely possible explanation for the faulty results? - ANSWER-The data collection was not accurate Ricardo is p...

Explain the overview of the sea phages lab and what we end you are trying to accomplish. - ANSWER-The goal of the sea phages lab is to isolate viruses (phages) there in fact bacterial host and sequence the genome of the purified phages. The sea phages lab is a discovery-based undergraduate research ...

Inductive reasoning goes from a set of specific observation to general conclusions. Used in discovery science. - ANSWER-What is inductive reasoning? In general Every animal that scientist have looked at is made up of cells, therefore all animals have cells. student always late - next class stude...

November 8 1895 - ANSWER-When were x-rays discovered? Wilhelm Roentgen discovered x-rays while working in his modest laboratory at the university. Barium Platinocyanide - ANSWER-Using a low-output Lenard tube wrapped in cardboard and tinfoil, so that no visible light emanated, showing the flu...

amastia ay-MAS-tee-ah a / mast / ia no/ breast/ condition - ANSWER-absence of a breast cervical dysplasia SER-vih-kal dis-PLAY-zhah - ANSWER-bad formation of cervical cells colpoptosis KOL-pawp-TOH-sis colpo / pt / osis vagina/ droop/ condition - ANSWER-downward displacement...