Extracellular Matrix Packaged Exams Latest Questions and Answers with complete solution

The ECM is primarily composed of --? - Answer-specific ECM glycoproteins cells in tissues are physically connected to neighboring cells and/or ---? - Answer-the extracellular matrix what are some functions of the ECM? - Answer-tensile strength, incompressibility and elasticity what component of t...

Cancerous tumors of breast tissue typically have _____ collagen present in the ECM compared to healthy tissue - more. Cancerous tumors of breast tissue produce ECMs that are _____ compared to healthy ECM. - stiffer. Based on trichrome staining, which tissue contained the most collagen? - IDC tum...

what is the ECM? - Answer-the non-cellular component present within all tissues and organs what is the ECM composed of? - Answer--composed of collagen I and elastin -fundamentally composed of water, proteins and polysaccharides -a complex network of proteins and polysaccharides what is the ECM s...

Glycosaminoglycans (GAGs) - -Unbranched - (-) Charged polysaccharide chains Proteoglycans - 95% sugar -Large Molecules that provide: Cushion and physical barriers -Synthesized in ER or plasma membrane -Release from cell or bound to membrane Fibrous Proteins (Collagens) - Maintain tissue integr...

Aspects of the Bone ECM? - Answer-Organic and Inorganic What is found in the organic part of ECM? - Answer-Flexibility, Type I collagen and proteoglycan. There are also osteoectin, osteocalcin, and bone sialoprotein What do osteonectin, osteocalcin, and bone sialoprotein do respectively? What are...

What is the ying of the ECM? - Collagens What is the yang of the ECM - Glycosaminoglycans -GAGs What is another main component of the ECM - proteoglycans Describe the structure of collagen - Contains 3 alpha chain polypeptides which intertwine to form a triple helix How does collagen have high ...

Extracellular Matrix (ECM) - -relatively stable structural material that lies under epithelia & that surrounds connective tissue cells -can be divided into 2 structural components: fibers & amorphous ground substance Fibers - -an aggregate of fibrils -1-10 um diameter (largest) -can be divided ...

Tissues made up of two things - -cells -extracellular matrix (extracellular space) What is the extracellular matrix - -complex network of macromolecules in the extracellular space between cells What is the Extracellular matrix made of? - -polysaccharides and proteins that are made and scripted ...

Extracellular Matrix (ECM) - The ECM provides structural support to the cell and also plays a role in cell signaling. -Components: • Collagen • Glycoproteins (proteins with an oligosaccharide) • GAGs (long polysaccharide chains with amino sugars) • Proteoglycans (a core protein with on...

extracellular matrix - serves as physical structure to stabilize cells, molecular barrier against cell migration during infection and metastasis type IV collagenases - breakdown type IV collegen, epithelial-derived cancer cells cannot metastasize until they express these proteinases, Clostridium ...