SBCP EXAMS BUNDLE WITH Questions Solved 100% Correct

Rectal Route - Answer · Useful if person is vomiting or unconscious · 50% of absorbed drug will bypass the liver · Absorption is often irregular and incomplete · E.g. antiemetics Parenteral (outside the Intestines) 1 route are: - Answer Intra-venous Intra-muscular Sub-cutaneous Parenteral...

What increases the likelihood of drugs exacerbating symptoms Multiple medial conditions Drug interactions that are harmful are - Answer Wargarin and aspirin for headaches can increase the chance of bleeding What increases the likelihood for comorbidities - Answer Older age If a patient is more ...

Causes of bacterial diarrhoea - Answer Campylobacter (assoc. with Guillain Barre) Salmonella Shigella E.coli Vibrio cholera Toxic ingesting bacteria - Answer Clostridium perfringens (Gravies) Bacillus cereus (reheated rice) S.aureus Clostridium Botulinum

Pale focus on eosinophilic hyaline surround by lymphocytes and macrophages - Answer Aschoff bodies (Rheumatic fever) Anitschkow cells - Answer Contained in Aschoff bodies in myocarditis of acute rheumatic fever Ectocervix - Answer a portion of the canal of the uterine cervix that is lined with ...

Benign slow growing tumour on surface, age 40-60, dense cortical bone on hist, exicise - Answer Osteoma Small painful tumour, worse at night, affects young males, treat with radio frequency ablation - Answer Osteoid osteoma Large mass affecting males, pain and swelling, vertebral column. Well de...

Eczema around nipple - Answer Paget's disease Paget's disease of nipple - Answer Ductal carcinoma in situ Microcalcifications, no necrosis, premenopausal, bilateral - Answer Lobular carcinoma in situe/ISLN Tubule formation, cells in nests/islands - Answer Invasive ductal carcinoma

The minor pathway (CYP450 2E1) - Answer Produces toxin --> detoxified by glutathione in liver - but fixed quantity/ 24 hrs Excess toxins damage liver and encourages inflammation --> reversible or irreversible damage Acetylcysteine admin IV <8hrs replaces glutathione Heavy metals includ...

A drug given by which route would be associated with the greatest first pass effect - Answer Oral Anastasia takes a single dose of 1500mg of paracetamol, if the half life of the drug is two hours, approximately how many hours will it be before her plasma concentration of the drug falls to 375mg?...

Infants less than 1 year old are more sensitive to drug doses than older children, because infants: - Answer Have a slower rate of drug metabolism Epilepsy medications must be continued while a woman is pregnant, as seizures can be harmful for the baby. Which of the following changes that occur d...

Osteoporosis biochemistry - Answer Calcium, phosphate and ALP normal if no fractures ALP increased with fractures ALP - Answer Bone cancer and metastases Hyponatraemia - Answer SIADH - SCC of lung Lactate dehydrogenase - Answer Haematological malignancy Total protein - Answer Myeloma Ferritin ...

Causes of bacterial diarrhoea - Answer Campylobacter (assoc. with Guillain Barre) Salmonella Shigella E.coli Vibrio cholera Toxic ingesting bacteria - Answer Clostridium perfringens (Gravies) Bacillus cereus (reheated rice) S.aureus Clostridium Botulinum