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  3. Anglia Ruskin University (ARU)
  4.  
  5. BSc
  6.  
  7. Biomedical Science (MOD002739)

Summary

Summary Fluid and Electrolyte Balance
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Kidney, changes in blood volume, pressure triggers RAAS, RAAS, antidiuretic hormone, mechanism of action of ADH, Aldosterone, disorders of water balance, dehydration, haemorrhage, blood loss, hypovolaemic shock, blood pH levels, acid-base balance, respiratory acidosis, respiratory alkalosis

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  • May 4, 2021
  • 3
  • 2020/2021
  • Summary

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Fluid and Electrolye Balance
Kidney blood volume or
pressure
 Primary organ involved in
 When person sweats
osmoregulation
excessively, or is
 Fluid balance
dehydrated
 Alcohol inhibits production of
ADH
Mechanism of action of ADH
 Primary function
 Decrease loss of water
from kidneys
 Reduces concentration
of electrolytes
 Increases blood
pressure
 Released from pituitary
Changes in Blood Volume
gland to targets:
and Pressure Trigger RAAS
 Collection tubules in
Granular cells of juxtaglomerular kidneys
apparatus releases renin in  Membrane
response to: more
permeable to
 Sympathetic nervous system
water
simulation
(increases
 Decreased filtrate osmolarity
water
 Decreased stretch
reabsorption)
 Due to decreased
 Decreased urine
blood pressure
output
 Sweat glands
RAAS  Decrease
perspiration to
Renin Angiotensin Aldosterone conserve water
System  Arterioles
 Smooth muscle
Antidiuretic Hormone constricts
 Increases blood
 Synthesized in pressure
hypothalamus, stored in and
released from posterior Aldosterone
pituitary when hypothalamic
 Synthesized in adrenal
osmoreceptors stimulated
cortex
 Released in response to:
 Zone glomerulosa
 Rise in blood
 Controls levels of Na+, K+
concentration of
ions in extracellular fluids
electrolytes, fall in

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