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Anxiety clinical summary

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Summary of 2 pages for the course pharmacy at UBir (Lecture notes)

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  • June 8, 2021
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  • 2020/2021
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Anxiety
https://cks.nice.org.uk/topics/generalized-anxiety-disorder/ [NICE guidance ref]

Definition: Generalized anxiety disorder (GAD) is characterized by disproportionate,
pervasive, uncontrollable, and widespread worry and a range of somatic, cognitive, and
behavioural symptoms that occur on a continuum of severity.
 Onset of symptoms is insidious, often unremitting, and can be lifelong.
 While some people will present with obvious anxiety, others will initially present
with somatic symptoms such as muscle tension or insomnia.

Diagnosis:
The GAD-2 scale is used for diagnoses in primary practise whilst the GAD-7 scale is used by
specialists.


 Score 3 or more consider anxiety

 The DSM-V diagnostic criteria for GAD include:
o At least 6 months of excessive, difficult to control worry about everyday
issues, that is disproportionate to any inherent risk, and causes distress, or
impairment.
o The worry is not confined to features of another mental disorder, or as a
result of substance abuse, or a general medical condition.
o The person experiences at least 3 of the following symptoms most of the
time: restlessness/nervousness, being easily fatigued, poor concentration,
irritability, muscle tension, or sleep disturbance.
 The ICD-10 diagnostic criteria for GAD include:
o Anxiety which is generalized and persistent but not restricted to, or even
strongly predominating in, any particular environmental circumstances.
o Variable dominant symptoms including persistent nervousness, trembling,
muscle tension, sweating, lightheadedness, palpitations, dizziness, and
epigastric discomfort.
o Expression of fears such as that the person or a relative will shortly become ill
or have an accident

Management:
 Ask about the use of:
o OTC/prescribed medicines which can cause anxiety-albutamol, theophylline,
beta-blockers, herbal medicines (including ma huang, St. John's wort,
ginseng, guarana, belladonna), corticosteroids, and some antidepressants.
o Alcohol or illicit substances that can cause anxiety acutely and in withdrawal.


This must be a combination of both pharmacological and non-pharmacological
treatments [CBT].

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