Lecture notes
Table of Amino Acid Properties
A table showing the charge, polarity, typical pKA and any notes mentioned in the respective biochemistry module lectures and textbooks for year 1.
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Name & Structure Polarity Charge Hydrophilic/ 3 ionisable groups Typical Notesabbreviations hydrophobic group pKa
Alanine, Ala, A Non-polar Neutral Hydrophobic No Terminal
alpha
carboxyl
group pKa
is 3.1
Arginine, Arg, R Polar Positive Hydrophilic Yes 12.5
Asparagine, Polar Neutral Hydrophilic Yes
Asn, N
Aspartic acid, Polar Negative Hydrophilic Yes 3.9
Asp, D
Cysteine, Cys, C Polar Neutral Hydrophilic Yes 8.3 Contains a free thiol (SH) group so can
form covalent di-sulfide bonds. It is a
good ligand.
Glutamine, Gln, Polar Neutral Hydrophilic Yes
Q
Glutamic acid, Polar Negative Hydrophilic Yes 4.3
Glu, E (average
with asp =
4.1)
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