Lecture notes
Electrolyte Disorders
- Module
- Blood Science (6H5Z1003)
- Institution
- Manchester Metropolitan University (MMU)
Lecture notes on Electrolyte Disorders
[Show more]
Content preview
Electrolytes have various functions:1. Maintenance of body pH
2. Cofactors in enzyme reactions
3. Water balance by maintaining osmotic
pressure
4. Correct functioning of muscles and nerves
5. Oxidation-reduction reactions
Osmolality - indicator of fluid balance:
- A measure of the osmotic concentration
usually expressed as moles of solute per kg of
solvent (mOsm/kg)
- 285 - 295 mOsm/kg
Regulation of fluid distribution:
1. Osmosis
a. Cells don't burst
b. 20-40% of the daily ATP generation consumed in trying to regulate ionic gradient
2. Maintaining electrical neutrality
a.
b. Expressed in mEq/L
c. Na+ 1 mmol/L = 1 mEq/L
d. Ca2+ 1 mmol/L = 2 mEq/L
Distribution of water in the body compartments: The body has 2 major fluid compartments:
Na+ regulates fluid flux between ECF and ICF
- Increase in Na+ ISF - H2O moves out from cells
- Decrease in Na+ ISF - cells overhydrate
, Loss of pure water from ECF:
- Ions can’t be exchanged to balance the difference
- Water movement will balance the difference
Renal regulation - juxtaglomerular apparatus
The benefits of buying summaries with Stuvia:
Guaranteed quality through customer reviews
Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.
Quick and easy check-out
You can quickly pay through credit card for the summaries. There is no membership needed.
Focus on what matters
Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!
Frequently asked questions
What do I get when I buy this document?
You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.
Satisfaction guarantee: how does it work?
Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.
Who am I buying these notes from?
Stuvia is a marketplace, so you are not buying this document from us, but from seller polinalobacheva. Stuvia facilitates payment to the seller.
Will I be stuck with a subscription?
No, you only buy these notes for £9.99. You're not tied to anything after your purchase.
Can Stuvia be trusted?
4.6 stars on Google & Trustpilot (+1000 reviews)
66475 documents were sold in the last 30 days
Founded in 2010, the go-to place to buy revision notes and other study material for 14 years now