This fact sheet will explain all you need to know regarding the safe administration of Neonatal Paracetamol suspension including dosage, pharmacodynamics, side effects, interactions, contraindications and administration. Perfect for student midwives!
BASICS: DOSAGE:
• Analgesic, non-opioid • Calculated as 10mg per kg for neonates
• ‘Calpol’ • 4 hourly
• Mild to moderate pain, pyrexia DRUG CALCULATION:
• POM however sold as GSL in specified 10 x BW = amount needed per dose
amounts
Amount needed per dose
• Oral suspension
/ amount (mg) bottle X preparation (mls)
Mls needed to give baby
CONTRAINDICATIONS: SIDE EFFECTS:
• Hypersensitivity • RARE
• Hepatic and Renal Disease • Rashes
• Alcohol dependence - not for infant lol • Blood disorders
INTERACTIONS: • Overdose can lead to liver damage
• Anticoagulants - prolonged use increases • Pancreatitis with prolonged use
effect of warfarin
• Cholestyramine - reduces absorption
• Metoclopramide - enhances affects
FETAL RISK: BREASTFEEDING:
• No known associated risk found in • Short courses only - amount secreted too
epidemiological studies in human small to be harmful
pregnancy • No controlled study data available and
taken by a large number of women with no
observed increase in adverse reactions on
breastfed infants, therefore considered
safe.
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